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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNK2 All Species: 17.58
Human Site: S757 Identified Species: 38.67
UniProt: Q07912 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07912 NP_001010938.1 1038 114569 S757 T R P H V Q L S P A P P G E E
Chimpanzee Pan troglodytes XP_001170078 532 57840 A303 R H G A F S S A S D V W M F G
Rhesus Macaque Macaca mulatta XP_001101686 1038 114517 S757 T R P H V Q L S P A P S G E E
Dog Lupus familis XP_545148 1041 114947 S759 T R P R G E L S P A P S G E E
Cat Felis silvestris
Mouse Mus musculus O54967 1055 116957 S772 T R P R V E L S P A P S G E E
Rat Rattus norvegicus Q5U2X5 1040 115050 S757 T R P R V G L S P A P L G E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517377 665 71250 V436 A V A F F P L V L L P Y P F F
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919038 1007 113912 G733 G D L S P V F G N E D D K E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9I7F7 1337 147458 L991 L Q R T L S K L A D F G D E A
Honey Bee Apis mellifera XP_396503 1302 145297 T854 N S W P S K S T N I Q Q P S A
Nematode Worm Caenorhab. elegans Q10925 1237 134472 S847 V Q K P V Q V S A P T H S N V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.4 98.5 94.3 N.A. 92.8 93.7 N.A. 38.3 N.A. N.A. 56.1 N.A. 25.1 32.4 27.1 N.A.
Protein Similarity: 100 34.4 98.8 95.7 N.A. 94.2 95.5 N.A. 45.8 N.A. N.A. 67.2 N.A. 40.6 47.3 41.3 N.A.
P-Site Identity: 100 0 93.3 73.3 N.A. 80 80 N.A. 13.3 N.A. N.A. 6.6 N.A. 6.6 0 20 N.A.
P-Site Similarity: 100 6.6 93.3 80 N.A. 86.6 80 N.A. 13.3 N.A. N.A. 6.6 N.A. 20 13.3 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 10 0 0 0 10 19 46 0 0 0 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 19 10 10 10 0 0 % D
% Glu: 0 0 0 0 0 19 0 0 0 10 0 0 0 64 46 % E
% Phe: 0 0 0 10 19 0 10 0 0 0 10 0 0 19 10 % F
% Gly: 10 0 10 0 10 10 0 10 0 0 0 10 46 0 10 % G
% His: 0 10 0 19 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 10 10 0 0 0 0 0 10 0 0 % K
% Leu: 10 0 10 0 10 0 55 10 10 10 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 19 0 0 0 0 10 0 % N
% Pro: 0 0 46 19 10 10 0 0 46 10 55 10 19 0 0 % P
% Gln: 0 19 0 0 0 28 0 0 0 0 10 10 0 0 0 % Q
% Arg: 10 46 10 28 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 0 10 0 10 10 19 19 55 10 0 0 28 10 10 0 % S
% Thr: 46 0 0 10 0 0 0 10 0 0 10 0 0 0 0 % T
% Val: 10 10 0 0 46 10 10 10 0 0 10 0 0 0 10 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _