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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP1
All Species:
21.21
Human Site:
S3217
Identified Species:
51.85
UniProt:
Q07954
Number Species:
9
Phosphosite Substitution
Charge Score:
0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07954
NP_002323.2
4544
504575
S3217
E
D
Y
I
E
F
A
S
L
D
G
S
N
R
H
Chimpanzee
Pan troglodytes
XP_515817
4636
518955
D3239
H
I
E
F
S
N
M
D
G
S
H
R
H
K
V
Rhesus Macaque
Macaca mulatta
XP_001117994
4592
514768
D3195
H
I
E
F
S
N
M
D
G
S
H
R
H
K
V
Dog
Lupus familis
XP_538245
4526
502835
S3199
E
D
Y
I
E
F
A
S
L
D
G
S
N
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZX7
4545
504723
S3218
E
D
Y
I
E
F
A
S
L
D
G
S
N
R
H
Rat
Rattus norvegicus
P98158
4660
519258
D3395
L
G
Y
I
E
F
S
D
L
E
G
H
H
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
S3214
E
D
Y
I
E
F
A
S
L
D
G
S
N
R
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920591
4547
508513
S3220
E
D
Y
I
A
F
A
S
L
D
G
S
N
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
D3510
L
N
E
I
G
F
M
D
F
D
G
N
G
R
R
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
S3159
E
D
R
I
E
S
V
S
W
N
G
T
N
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
60
96.5
N.A.
98
37.2
N.A.
N.A.
86.7
N.A.
76.2
N.A.
N.A.
N.A.
31.6
44.7
Protein Similarity:
100
74.1
74.6
97.5
N.A.
98.9
53
N.A.
N.A.
93
N.A.
86.2
N.A.
N.A.
N.A.
48.3
61.3
P-Site Identity:
100
0
0
100
N.A.
100
53.3
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
33.3
60
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
73.3
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
46.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
50
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
60
0
0
0
0
0
40
0
60
0
0
0
0
0
% D
% Glu:
60
0
30
0
60
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
20
0
70
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
10
0
0
0
20
0
80
0
10
0
0
% G
% His:
20
0
0
0
0
0
0
0
0
0
20
10
30
0
70
% H
% Ile:
0
20
0
80
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% K
% Leu:
20
0
0
0
0
0
0
0
60
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
30
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
20
0
0
0
10
0
10
60
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
20
0
80
10
% R
% Ser:
0
0
0
0
20
10
10
60
0
20
0
50
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _