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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP1
All Species:
18.48
Human Site:
T1790
Identified Species:
45.19
UniProt:
Q07954
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07954
NP_002323.2
4544
504575
T1790
R
S
Q
L
G
K
A
T
A
L
A
I
M
G
D
Chimpanzee
Pan troglodytes
XP_515817
4636
518955
K1811
L
E
V
I
E
S
M
K
E
E
L
T
K
A
T
Rhesus Macaque
Macaca mulatta
XP_001117994
4592
514768
T1771
E
S
M
K
E
E
L
T
K
A
T
A
L
T
I
Dog
Lupus familis
XP_538245
4526
502835
T1772
R
S
Q
L
G
K
A
T
A
L
A
I
M
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZX7
4545
504723
T1791
R
S
Q
L
G
K
A
T
A
L
A
I
M
G
D
Rat
Rattus norvegicus
P98158
4660
519258
H1960
E
R
M
I
L
V
H
H
L
A
H
P
W
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
T1788
K
S
Q
L
S
K
A
T
A
L
A
I
M
G
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920591
4547
508513
T1795
K
G
K
L
T
K
A
T
A
L
A
I
M
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
N2024
S
D
G
G
R
Q
P
N
G
L
A
F
Y
G
D
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
P1776
S
L
D
E
A
S
Q
P
S
A
I
T
V
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
60
96.5
N.A.
98
37.2
N.A.
N.A.
86.7
N.A.
76.2
N.A.
N.A.
N.A.
31.6
44.7
Protein Similarity:
100
74.1
74.6
97.5
N.A.
98.9
53
N.A.
N.A.
93
N.A.
86.2
N.A.
N.A.
N.A.
48.3
61.3
P-Site Identity:
100
0
13.3
100
N.A.
100
6.6
N.A.
N.A.
86.6
N.A.
73.3
N.A.
N.A.
N.A.
26.6
0
P-Site Similarity:
100
6.6
26.6
100
N.A.
100
13.3
N.A.
N.A.
93.3
N.A.
86.6
N.A.
N.A.
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
50
0
50
30
60
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
60
% D
% Glu:
20
10
0
10
20
10
0
0
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
10
10
10
30
0
0
0
10
0
0
0
0
70
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
20
0
0
0
0
0
0
10
50
0
0
10
% I
% Lys:
20
0
10
10
0
50
0
10
10
0
0
0
10
0
0
% K
% Leu:
10
10
0
50
10
0
10
0
10
60
10
0
10
0
10
% L
% Met:
0
0
20
0
0
0
10
0
0
0
0
0
50
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
10
0
0
0
10
0
0
10
% P
% Gln:
0
0
40
0
0
10
10
0
0
0
0
0
0
0
0
% Q
% Arg:
30
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
50
0
0
10
20
0
0
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
60
0
0
10
20
0
20
10
% T
% Val:
0
0
10
0
0
10
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _