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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP1
All Species:
23.33
Human Site:
T4500
Identified Species:
57.04
UniProt:
Q07954
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07954
NP_002323.2
4544
504575
T4500
A
L
D
P
D
K
P
T
N
F
T
N
P
V
Y
Chimpanzee
Pan troglodytes
XP_515817
4636
518955
T4592
G
P
L
T
A
G
P
T
N
Y
S
N
P
V
Y
Rhesus Macaque
Macaca mulatta
XP_001117994
4592
514768
T4548
G
P
L
T
A
G
P
T
N
Y
S
N
P
V
Y
Dog
Lupus familis
XP_538245
4526
502835
T4482
A
L
D
P
D
K
P
T
N
F
T
N
P
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZX7
4545
504723
T4501
A
L
D
P
D
K
P
T
N
F
T
N
P
V
Y
Rat
Rattus norvegicus
P98158
4660
519258
A4629
P
P
S
P
S
L
P
A
K
A
S
K
R
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
T4499
A
L
D
P
D
K
P
T
N
F
T
N
P
V
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920591
4547
508513
T4504
T
L
D
P
D
K
P
T
N
F
T
N
P
V
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
I4720
I
I
V
P
K
A
E
I
S
K
P
P
I
P
A
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
H4429
A
P
F
T
V
R
D
H
K
A
R
T
N
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
60
96.5
N.A.
98
37.2
N.A.
N.A.
86.7
N.A.
76.2
N.A.
N.A.
N.A.
31.6
44.7
Protein Similarity:
100
74.1
74.6
97.5
N.A.
98.9
53
N.A.
N.A.
93
N.A.
86.2
N.A.
N.A.
N.A.
48.3
61.3
P-Site Identity:
100
46.6
46.6
100
N.A.
100
13.3
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
60
60
100
N.A.
100
20
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
20
10
0
10
0
20
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
0
50
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
50
0
0
0
10
0
% F
% Gly:
20
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
10
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
10
50
0
0
20
10
0
10
0
0
0
% K
% Leu:
0
50
20
0
0
10
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
70
0
0
70
10
10
0
% N
% Pro:
10
40
0
70
0
0
80
0
0
0
10
10
70
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
10
0
10
0
0
% R
% Ser:
0
0
10
0
10
0
0
0
10
0
30
0
0
0
0
% S
% Thr:
10
0
0
30
0
0
0
70
0
0
50
10
0
0
10
% T
% Val:
0
0
10
0
10
0
0
0
0
0
0
0
0
70
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
70
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _