KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP1
All Species:
27.88
Human Site:
Y1587
Identified Species:
68.15
UniProt:
Q07954
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07954
NP_002323.2
4544
504575
Y1587
E
F
K
K
F
L
L
Y
A
R
Q
M
E
I
R
Chimpanzee
Pan troglodytes
XP_515817
4636
518955
Y1615
E
M
K
K
F
L
L
Y
A
R
R
S
E
I
R
Rhesus Macaque
Macaca mulatta
XP_001117994
4592
514768
Y1571
E
M
K
K
F
L
L
Y
A
R
R
S
E
I
R
Dog
Lupus familis
XP_538245
4526
502835
Y1569
E
F
K
K
F
L
L
Y
A
R
Q
M
E
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZX7
4545
504723
Y1588
E
F
K
K
F
L
L
Y
A
R
Q
M
E
I
R
Rat
Rattus norvegicus
P98158
4660
519258
S1751
G
D
Q
P
F
L
M
S
V
R
D
N
I
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
Y1585
E
F
K
K
F
L
L
Y
A
R
Q
M
E
I
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920591
4547
508513
Y1590
E
Y
R
Q
F
L
L
Y
A
R
Q
I
E
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
E1811
I
E
M
N
S
A
S
E
K
E
T
P
V
L
A
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
I1570
N
D
T
V
F
F
V
I
S
R
P
T
D
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
60
96.5
N.A.
98
37.2
N.A.
N.A.
86.7
N.A.
76.2
N.A.
N.A.
N.A.
31.6
44.7
Protein Similarity:
100
74.1
74.6
97.5
N.A.
98.9
53
N.A.
N.A.
93
N.A.
86.2
N.A.
N.A.
N.A.
48.3
61.3
P-Site Identity:
100
80
80
100
N.A.
100
26.6
N.A.
N.A.
100
N.A.
73.3
N.A.
N.A.
N.A.
0
26.6
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
40
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
6.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
70
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
0
0
0
0
0
10
0
10
0
0
% D
% Glu:
70
10
0
0
0
0
0
10
0
10
0
0
70
0
0
% E
% Phe:
0
40
0
0
90
10
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
0
0
0
10
10
90
0
% I
% Lys:
0
0
60
60
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
80
70
0
0
0
0
0
0
10
0
% L
% Met:
0
20
10
0
0
0
10
0
0
0
0
40
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
10
10
0
0
0
% P
% Gln:
0
0
10
10
0
0
0
0
0
0
50
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
90
20
0
0
0
80
% R
% Ser:
0
0
0
0
10
0
10
10
10
0
0
20
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
10
10
0
0
0
% T
% Val:
0
0
0
10
0
0
10
0
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _