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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP1
All Species:
23.64
Human Site:
Y4476
Identified Species:
57.78
UniProt:
Q07954
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07954
NP_002323.2
4544
504575
Y4476
G
N
P
T
Y
K
M
Y
E
G
G
E
P
D
D
Chimpanzee
Pan troglodytes
XP_515817
4636
518955
Y4535
G
N
P
S
Y
N
M
Y
E
V
D
H
D
H
N
Rhesus Macaque
Macaca mulatta
XP_001117994
4592
514768
Y4491
G
N
P
S
Y
N
M
Y
E
V
D
H
D
H
S
Dog
Lupus familis
XP_538245
4526
502835
Y4458
G
N
P
T
Y
K
M
Y
E
G
G
E
P
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZX7
4545
504723
Y4477
G
N
P
T
Y
K
M
Y
E
G
G
E
P
D
D
Rat
Rattus norvegicus
P98158
4660
519258
K4614
A
E
M
D
S
E
V
K
D
A
V
A
V
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
Y4475
G
N
P
T
Y
K
M
Y
E
G
E
P
D
D
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920591
4547
508513
Y4480
G
N
P
A
Y
K
I
Y
E
G
E
P
D
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
I4705
P
T
F
D
Q
D
E
I
E
L
K
T
A
D
E
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
S4407
G
N
P
T
F
K
Y
S
R
Q
V
N
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
60
96.5
N.A.
98
37.2
N.A.
N.A.
86.7
N.A.
76.2
N.A.
N.A.
N.A.
31.6
44.7
Protein Similarity:
100
74.1
74.6
97.5
N.A.
98.9
53
N.A.
N.A.
93
N.A.
86.2
N.A.
N.A.
N.A.
48.3
61.3
P-Site Identity:
100
46.6
46.6
100
N.A.
100
0
N.A.
N.A.
80
N.A.
66.6
N.A.
N.A.
N.A.
13.3
33.3
P-Site Similarity:
100
60
53.3
100
N.A.
100
20
N.A.
N.A.
80
N.A.
73.3
N.A.
N.A.
N.A.
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
0
0
10
0
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
0
10
0
0
10
0
20
0
40
60
50
% D
% Glu:
0
10
0
0
0
10
10
0
80
0
20
30
10
10
20
% E
% Phe:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
80
0
0
0
0
0
0
0
0
50
30
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
20
0
20
0
% H
% Ile:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
60
0
10
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
60
0
0
0
0
0
0
0
0
% M
% Asn:
0
80
0
0
0
20
0
0
0
0
0
10
0
0
10
% N
% Pro:
10
0
80
0
0
0
0
0
0
0
0
20
30
0
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
20
10
0
0
10
0
0
0
0
0
0
10
% S
% Thr:
0
10
0
50
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
20
20
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
70
0
10
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _