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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS1 All Species: 19.09
Human Site: S205 Identified Species: 32.31
UniProt: Q07955 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07955 NP_001071634.1 248 27745 S205 R S P S Y G R S R S R S R S R
Chimpanzee Pan troglodytes Q5R1W5 221 25469 S179 K S S S V S R S R S R S R S R
Rhesus Macaque Macaca mulatta XP_001103473 406 44532 S358 R S P S Y G R S R S R S R S R
Dog Lupus familis XP_853057 292 32007 V205 L K L M G P E V Q V M E D L D
Cat Felis silvestris
Mouse Mus musculus Q9D0B0 222 25643 T178 F R S H E G E T S Y I R V Y P
Rat Rattus norvegicus Q5PPI1 221 25480 T177 F R S H E G E T S Y I R V Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517964 202 22532 R160 S P S Y G R S R S R S R S R S
Chicken Gallus gallus Q5ZML3 257 28042 S205 R S P S Y G R S R S R S V V V
Frog Xenopus laevis NP_001088400 230 25898 E187 K F R S H E G E T S Y I R V S
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 G202 G P R S P S Y G R S R S R S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 S219 S S R S R S R S R R R S R S R
Honey Bee Apis mellifera XP_393525 248 28355 E206 S G D R G R S E D R E R G R S
Nematode Worm Caenorhab. elegans Q9NEW6 258 28662 G207 S G G G S G G G G R D R S R S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 S215 R S Y S K S R S R S R G R S V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.2 60.5 66.4 N.A. 64.1 64.1 N.A. 77 82 65.3 96.3 N.A. 23.6 68.5 60 N.A.
Protein Similarity: 100 37.9 60.8 72.5 N.A. 72.5 72.1 N.A. 78.2 85.9 76.2 97.5 N.A. 35.6 77.4 70.1 N.A.
P-Site Identity: 100 73.3 100 0 N.A. 6.6 6.6 N.A. 0 80 20 53.3 N.A. 66.6 0 6.6 N.A.
P-Site Similarity: 100 80 100 6.6 N.A. 13.3 13.3 N.A. 0 80 33.3 53.3 N.A. 66.6 0 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 50.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 59 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 8 0 8 0 8 0 8 % D
% Glu: 0 0 0 0 15 8 22 15 0 0 8 8 0 0 0 % E
% Phe: 15 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 15 8 8 22 43 15 15 8 0 0 8 8 0 0 % G
% His: 0 0 0 15 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 15 8 0 0 0 % I
% Lys: 15 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 15 22 0 8 8 0 0 0 0 0 0 0 0 15 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 29 15 22 8 8 15 43 8 50 29 50 36 50 22 36 % R
% Ser: 29 43 29 58 8 29 15 43 22 50 8 43 15 43 29 % S
% Thr: 0 0 0 0 0 0 0 15 8 0 0 0 0 0 0 % T
% Val: 0 0 0 0 8 0 0 8 0 8 0 0 22 15 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 8 22 0 8 0 0 15 8 0 0 15 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _