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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS1 All Species: 21.21
Human Site: Y189 Identified Species: 35.9
UniProt: Q07955 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q07955 NP_001071634.1 248 27745 Y189 S H E G E T A Y I R V K V D G
Chimpanzee Pan troglodytes Q5R1W5 221 25469 S163 R S R S T S K S R S A R R S K
Rhesus Macaque Macaca mulatta XP_001103473 406 44532 Y342 S H E G E T A Y I R V K V D G
Dog Lupus familis XP_853057 292 32007 N189 S H E F C L F N R E K L P T S
Cat Felis silvestris
Mouse Mus musculus Q9D0B0 222 25643 A162 R K E D M E Y A L R K L D D T
Rat Rattus norvegicus Q5PPI1 221 25480 A161 R K E D M E Y A L R K L D D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517964 202 22532 I144 H E G E T A Y I R V K V D G P
Chicken Gallus gallus Q5ZML3 257 28042 Y189 S H E G E T A Y I R V K V D G
Frog Xenopus laevis NP_001088400 230 25898 Y171 I R K E D M E Y A L R K L D D
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 T186 F R S H E G E T A Y I R V K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 S203 R S G G G G G S G R G R S R S
Honey Bee Apis mellifera XP_393525 248 28355 Y190 S H E G E V A Y I R V K E D H
Nematode Worm Caenorhab. elegans Q9NEW6 258 28662 Y191 S H E G E T A Y I R V R E D N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 K199 V R E Y D S R K D S R S P S R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.2 60.5 66.4 N.A. 64.1 64.1 N.A. 77 82 65.3 96.3 N.A. 23.6 68.5 60 N.A.
Protein Similarity: 100 37.9 60.8 72.5 N.A. 72.5 72.1 N.A. 78.2 85.9 76.2 97.5 N.A. 35.6 77.4 70.1 N.A.
P-Site Identity: 100 0 100 20 N.A. 20 20 N.A. 0 100 20 13.3 N.A. 13.3 80 80 N.A.
P-Site Similarity: 100 13.3 100 20 N.A. 26.6 26.6 N.A. 0 100 40 26.6 N.A. 20 80 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 50.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 59 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 36 15 15 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 15 15 0 0 0 8 0 0 0 22 58 8 % D
% Glu: 0 8 65 15 43 15 15 0 0 8 0 0 15 0 0 % E
% Phe: 8 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 15 43 8 15 8 0 8 0 8 0 0 8 22 % G
% His: 8 43 0 8 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 0 0 0 0 0 8 36 0 8 0 0 0 0 % I
% Lys: 0 15 8 0 0 0 8 8 0 0 29 36 0 8 8 % K
% Leu: 0 0 0 0 0 8 0 0 15 8 0 22 8 0 0 % L
% Met: 0 0 0 0 15 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 29 22 8 0 0 0 8 0 22 58 15 29 8 8 8 % R
% Ser: 43 15 8 8 0 15 0 15 0 15 0 8 8 15 15 % S
% Thr: 0 0 0 0 15 29 0 8 0 0 0 0 0 8 15 % T
% Val: 8 0 0 0 0 8 0 0 0 8 36 8 29 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 22 43 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _