KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP1
All Species:
20.61
Human Site:
S223
Identified Species:
41.21
UniProt:
Q07960
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07960
NP_004299.1
439
50436
S223
F
L
K
S
T
Q
K
S
P
A
T
A
P
K
P
Chimpanzee
Pan troglodytes
XP_508398
562
63325
S346
F
L
K
S
T
Q
K
S
P
A
T
A
P
K
P
Rhesus Macaque
Macaca mulatta
XP_001101907
504
57584
S288
F
L
K
S
T
Q
K
S
P
A
T
A
P
K
P
Dog
Lupus familis
XP_851463
698
78707
G391
K
L
R
S
L
H
K
G
R
S
S
P
P
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5FWK3
439
50392
S223
F
L
K
S
T
Q
K
S
P
A
T
A
P
K
P
Rat
Rattus norvegicus
NP_001101217
439
50604
S223
F
L
K
S
T
Q
K
S
P
A
T
A
P
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426422
437
50382
P224
Y
L
R
S
L
Q
K
P
S
Q
V
P
Q
K
P
Frog
Xenopus laevis
NP_001086509
435
50336
T224
L
I
R
S
N
M
K
T
P
V
P
S
Q
K
S
Zebra Danio
Brachydanio rerio
NP_001017781
434
49569
P223
K
I
R
L
S
L
K
P
S
V
V
P
G
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTU3
476
54951
P249
K
L
N
P
S
R
K
P
S
T
P
P
P
S
S
Honey Bee
Apis mellifera
XP_624226
496
56427
K285
Q
L
M
L
K
N
K
K
N
L
P
T
S
P
P
Nematode Worm
Caenorhab. elegans
NP_001022390
444
50636
N232
K
S
F
S
T
Q
S
N
R
P
E
T
P
P
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
86.1
30.5
N.A.
96.5
94.5
N.A.
N.A.
81
74.4
61.7
N.A.
33.1
43.5
37.8
N.A.
Protein Similarity:
100
77.9
86.3
42.8
N.A.
97.7
97
N.A.
N.A.
89.5
86.7
75.1
N.A.
53.1
61.6
57.6
N.A.
P-Site Identity:
100
100
100
26.6
N.A.
100
100
N.A.
N.A.
40
26.6
6.6
N.A.
20
20
26.6
N.A.
P-Site Similarity:
100
100
100
46.6
N.A.
100
100
N.A.
N.A.
53.3
53.3
26.6
N.A.
33.3
20
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
42
0
42
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
42
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
34
0
42
0
9
0
92
9
0
0
0
0
0
59
9
% K
% Leu:
9
75
0
17
17
9
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
9
0
9
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
25
50
9
25
34
67
25
59
% P
% Gln:
9
0
0
0
0
59
0
0
0
9
0
0
17
0
0
% Q
% Arg:
0
0
34
0
0
9
0
0
17
0
0
0
0
0
0
% R
% Ser:
0
9
0
75
17
0
9
42
25
9
9
9
9
9
17
% S
% Thr:
0
0
0
0
50
0
0
9
0
9
42
17
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
17
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _