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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP24A1
All Species:
23.03
Human Site:
Y93
Identified Species:
50.67
UniProt:
Q07973
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07973
NP_000773.2
514
58875
Y93
L
V
E
Y
H
K
K
Y
G
K
I
F
R
M
K
Chimpanzee
Pan troglodytes
XP_001154704
454
51614
Y93
L
V
E
Y
H
K
K
Y
G
K
I
F
R
M
K
Rhesus Macaque
Macaca mulatta
XP_001103470
811
88801
Y375
G
Q
K
H
T
Q
E
Y
G
K
I
F
K
S
H
Dog
Lupus familis
XP_543059
514
59110
Y93
L
A
E
Y
H
K
K
Y
G
K
I
F
R
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q64441
514
59435
Y93
L
A
E
Y
H
K
K
Y
G
Q
I
F
R
M
K
Rat
Rattus norvegicus
Q09128
514
59430
Y93
L
A
E
Y
H
K
K
Y
G
Q
I
F
R
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509535
444
51404
F92
W
Q
R
V
R
S
A
F
Q
K
K
L
M
K
P
Chicken
Gallus gallus
NP_990310
508
58110
L104
V
H
I
G
A
P
C
L
L
E
S
L
Y
R
R
Frog
Xenopus laevis
NP_001087098
542
61748
Y106
Q
L
N
Y
K
K
M
Y
G
P
L
W
R
S
E
Zebra Danio
Brachydanio rerio
NP_001082927
505
57264
L108
V
H
I
G
S
P
C
L
L
E
A
L
Y
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5L3
589
65883
K143
E
L
H
V
N
Y
G
K
M
A
K
V
G
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82
23.5
89.3
N.A.
82.8
83
N.A.
66.9
68.4
31.9
63.2
N.A.
27.3
N.A.
N.A.
N.A.
Protein Similarity:
100
84.2
38.2
93.7
N.A.
90.8
90.4
N.A.
76.4
80.3
52.5
77.4
N.A.
46.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
33.3
93.3
N.A.
86.6
86.6
N.A.
6.6
0
33.3
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
66.6
93.3
N.A.
93.3
93.3
N.A.
13.3
20
60
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
28
0
0
10
0
10
0
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
46
0
0
0
10
0
0
19
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
55
0
0
0
% F
% Gly:
10
0
0
19
0
0
10
0
64
0
0
0
10
10
0
% G
% His:
0
19
10
10
46
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
19
0
0
0
0
0
0
0
55
0
0
0
0
% I
% Lys:
0
0
10
0
10
55
46
10
0
46
19
0
10
10
55
% K
% Leu:
46
19
0
0
0
0
0
19
19
0
10
28
0
0
10
% L
% Met:
0
0
0
0
0
0
10
0
10
0
0
0
10
46
0
% M
% Asn:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
19
0
0
0
10
0
0
0
0
10
% P
% Gln:
10
19
0
0
0
10
0
0
10
19
0
0
0
0
0
% Q
% Arg:
0
0
10
0
10
0
0
0
0
0
0
0
55
19
10
% R
% Ser:
0
0
0
0
10
10
0
0
0
0
10
0
0
19
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
19
19
0
19
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
55
0
10
0
64
0
0
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _