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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTN3
All Species:
36.36
Human Site:
S298
Identified Species:
100
UniProt:
Q08043
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08043
NP_001095.1
901
103241
S298
E
E
Y
E
K
L
A
S
E
L
L
E
W
I
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109839
901
103277
S298
E
E
Y
E
K
L
A
S
E
L
L
E
W
I
R
Dog
Lupus familis
XP_852336
901
103273
S298
E
E
Y
E
K
L
A
S
E
L
L
E
W
I
R
Cat
Felis silvestris
Mouse
Mus musculus
O88990
900
103024
S297
E
E
Y
E
K
L
A
S
E
L
L
E
W
I
R
Rat
Rattus norvegicus
Q9Z1P2
892
102942
S284
E
D
Y
E
K
L
A
S
D
L
L
E
W
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P20111
897
104257
S294
E
E
Y
E
R
L
A
S
E
L
L
E
W
I
R
Frog
Xenopus laevis
NP_001086492
896
103580
S293
E
E
Y
E
K
L
A
S
E
L
L
E
W
I
R
Zebra Danio
Brachydanio rerio
NP_571597
896
103549
S293
E
E
Y
E
K
L
A
S
E
L
L
E
W
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18091
924
107001
S316
E
E
Y
E
R
L
A
S
D
L
L
E
W
I
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
96.7
N.A.
97.1
76.4
N.A.
N.A.
78.5
82.6
81.6
N.A.
66.5
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
99.3
98.5
N.A.
98.4
88.5
N.A.
N.A.
89.5
91.9
91.4
N.A.
81
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
86.6
N.A.
N.A.
93.3
100
93.3
N.A.
86.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
100
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
0
23
0
0
0
0
0
0
% D
% Glu:
100
89
0
100
0
0
0
0
78
0
0
100
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% I
% Lys:
0
0
0
0
78
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
100
0
0
0
100
100
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Q
% Arg:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
89
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% W
% Tyr:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _