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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS1
All Species:
23.03
Human Site:
S186
Identified Species:
50.67
UniProt:
Q08116
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08116
NP_002913.3
209
23858
S186
Y
T
L
M
E
K
D
S
Y
P
R
F
L
K
S
Chimpanzee
Pan troglodytes
XP_001166272
182
20796
Y160
T
L
M
E
K
D
S
Y
P
R
F
L
K
S
D
Rhesus Macaque
Macaca mulatta
XP_001112975
209
23867
S186
Y
T
L
M
E
K
D
S
Y
P
R
F
L
K
S
Dog
Lupus familis
XP_545702
209
24148
S186
Y
T
L
M
E
K
D
S
Y
P
R
F
L
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JL25
209
24088
S186
Y
S
L
M
E
K
D
S
Y
P
R
F
L
K
S
Rat
Rattus norvegicus
P97844
162
18817
S139
Y
A
L
M
E
K
D
S
Y
P
R
F
L
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516459
252
29244
S229
Y
T
L
M
E
R
D
S
Y
P
R
F
L
K
S
Chicken
Gallus gallus
Q7SZC6
208
23504
P186
P
P
R
A
G
C
G
P
E
N
C
K
R
A
H
Frog
Xenopus laevis
A1A643
201
23280
P179
L
M
E
R
D
S
Y
P
R
F
L
K
S
E
I
Zebra Danio
Brachydanio rerio
Q6DGI0
174
20503
F152
E
K
D
S
Y
P
R
F
I
R
S
K
I
Y
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49808
169
19576
P147
L
M
Q
R
D
S
Y
P
R
F
L
A
S
N
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87
97.1
89
N.A.
86.5
70.8
N.A.
59.9
41.1
50.7
39.2
N.A.
N.A.
N.A.
32.5
N.A.
Protein Similarity:
100
87
97.6
93.7
N.A.
92.8
72.7
N.A.
71
59.3
66.5
54.5
N.A.
N.A.
N.A.
47.3
N.A.
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
93.3
0
0
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
93.3
N.A.
100
0
13.3
6.6
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
0
0
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
10
0
19
10
55
0
0
0
0
0
0
0
10
% D
% Glu:
10
0
10
10
55
0
0
0
10
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
19
10
55
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
19
% I
% Lys:
0
10
0
0
10
46
0
0
0
0
0
28
10
55
0
% K
% Leu:
19
10
55
0
0
0
0
0
0
0
19
10
55
0
0
% L
% Met:
0
19
10
55
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% N
% Pro:
10
10
0
0
0
10
0
28
10
55
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
10
19
0
10
10
0
19
19
55
0
10
0
0
% R
% Ser:
0
10
0
10
0
19
10
55
0
0
10
0
19
10
55
% S
% Thr:
10
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
55
0
0
0
10
0
19
10
55
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _