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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AES
All Species:
17.88
Human Site:
S176
Identified Species:
43.7
UniProt:
Q08117
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08117
NP_001121.2
197
21970
S176
L
G
S
Q
A
H
L
S
K
E
D
K
N
G
H
Chimpanzee
Pan troglodytes
XP_001153657
264
29144
S243
L
G
S
Q
A
H
L
S
K
E
D
K
N
G
H
Rhesus Macaque
Macaca mulatta
XP_001099930
264
29102
S243
L
G
S
Q
A
H
L
S
K
E
D
K
N
G
H
Dog
Lupus familis
XP_542182
447
47071
S426
L
G
S
Q
A
H
L
S
K
E
D
K
N
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q62441
773
83769
L182
A
L
G
G
Q
S
H
L
P
I
K
D
E
K
K
Rat
Rattus norvegicus
P63003
197
21981
S176
L
G
S
Q
T
H
L
S
K
E
D
K
N
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511916
767
82978
L176
A
L
G
G
Q
S
H
L
P
I
K
D
E
K
K
Chicken
Gallus gallus
NP_989568
773
83801
L182
A
L
G
G
Q
S
H
L
P
I
K
D
E
K
K
Frog
Xenopus laevis
O42470
197
22016
K177
G
S
Q
G
H
L
P
K
E
D
K
N
G
H
E
Zebra Danio
Brachydanio rerio
O13166
761
82441
P187
L
G
S
Q
P
H
L
P
A
K
D
E
K
N
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.6
69.6
44
N.A.
20.1
99.4
N.A.
21.5
20.1
89.8
20.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
71.5
70.8
44
N.A.
22.5
99.4
N.A.
23.4
22.5
93.9
22
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
0
93.3
N.A.
0
0
0
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
0
93.3
N.A.
0
0
13.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
0
40
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
60
30
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
50
0
10
30
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
60
30
40
0
0
0
0
0
0
0
0
10
50
0
% G
% His:
0
0
0
0
10
60
30
0
0
0
0
0
0
10
60
% H
% Ile:
0
0
0
0
0
0
0
0
0
30
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
50
10
40
50
10
30
30
% K
% Leu:
60
30
0
0
0
10
60
30
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
50
10
0
% N
% Pro:
0
0
0
0
10
0
10
10
30
0
0
0
0
0
0
% P
% Gln:
0
0
10
60
30
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
60
0
0
30
0
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _