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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AES
All Species:
31.21
Human Site:
S55
Identified Species:
76.3
UniProt:
Q08117
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08117
NP_001121.2
197
21970
S55
D
K
L
A
S
E
K
S
E
M
Q
R
H
Y
V
Chimpanzee
Pan troglodytes
XP_001153657
264
29144
S122
D
K
L
A
S
E
K
S
E
M
Q
R
H
Y
V
Rhesus Macaque
Macaca mulatta
XP_001099930
264
29102
A122
K
K
L
V
A
A
K
A
S
S
T
R
H
T
W
Dog
Lupus familis
XP_542182
447
47071
S305
D
K
L
A
S
E
K
S
E
M
Q
R
H
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
Q62441
773
83769
T61
E
K
L
A
S
E
K
T
E
M
Q
R
H
Y
V
Rat
Rattus norvegicus
P63003
197
21981
S55
D
K
L
A
S
E
K
S
E
M
Q
R
H
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511916
767
82978
R58
S
E
K
T
E
M
Q
R
H
Y
V
M
Y
Y
E
Chicken
Gallus gallus
NP_989568
773
83801
T61
E
K
L
A
S
E
K
T
E
M
Q
R
H
Y
V
Frog
Xenopus laevis
O42470
197
22016
S57
D
K
L
A
G
E
K
S
E
M
Q
R
H
Y
V
Zebra Danio
Brachydanio rerio
O13166
761
82441
T55
I
K
L
A
N
E
K
T
E
M
Q
R
H
Y
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.6
69.6
44
N.A.
20.1
99.4
N.A.
21.5
20.1
89.8
20.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
71.5
70.8
44
N.A.
22.5
99.4
N.A.
23.4
22.5
93.9
22
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
33.3
100
N.A.
86.6
100
N.A.
6.6
86.6
93.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
46.6
100
N.A.
100
100
N.A.
26.6
100
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
80
10
10
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
20
10
0
0
10
80
0
0
80
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
90
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
10
90
10
0
0
0
90
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
90
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
80
0
10
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
80
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
90
0
0
0
% R
% Ser:
10
0
0
0
60
0
0
50
10
10
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
30
0
0
10
0
0
10
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
10
90
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _