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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CA
All Species:
30.3
Human Site:
S469
Identified Species:
44.44
UniProt:
Q08209
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08209
NP_000935.1
521
58688
S469
S
P
Q
H
K
I
T
S
F
E
E
A
K
G
L
Chimpanzee
Pan troglodytes
XP_001168163
525
58994
S473
S
P
Q
H
K
I
T
S
F
E
E
A
K
G
L
Rhesus Macaque
Macaca mulatta
XP_001108447
533
60397
K486
I
T
S
F
E
E
A
K
G
L
D
R
I
N
E
Dog
Lupus familis
XP_535672
673
74856
S621
S
P
Q
H
K
I
T
S
F
E
E
A
K
G
L
Cat
Felis silvestris
Mouse
Mus musculus
P48453
525
59155
S479
S
P
P
H
R
I
C
S
F
E
E
A
K
G
L
Rat
Rattus norvegicus
P63329
521
58625
S469
S
P
Q
H
K
I
T
S
F
E
E
A
K
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507011
444
50170
R401
E
E
A
K
G
L
D
R
I
N
E
R
M
P
P
Chicken
Gallus gallus
P48463
309
35545
C266
I
F
S
A
P
N
Y
C
Y
R
C
G
N
Q
A
Frog
Xenopus laevis
NP_001080813
518
58366
S469
S
P
Q
H
K
I
T
S
F
E
E
A
K
G
L
Zebra Danio
Brachydanio rerio
NP_001017856
511
57796
P459
E
A
I
R
G
F
S
P
Q
H
K
I
T
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
S527
S
P
N
H
K
I
T
S
F
A
E
A
K
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
C277
A
P
N
Y
C
Y
R
C
G
N
V
A
A
I
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
E272
S
A
P
N
Y
C
G
E
F
D
N
A
G
A
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48484
321
36353
S278
R
Q
L
V
T
V
F
S
A
P
N
Y
C
G
E
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
N547
L
P
R
G
A
L
S
N
G
V
K
G
L
D
E
Red Bread Mold
Neurospora crassa
Q05681
558
63895
S502
G
I
K
N
A
I
S
S
F
E
D
A
R
K
V
Conservation
Percent
Protein Identity:
100
98.6
95.8
77.4
N.A.
83.2
99.6
N.A.
84.2
27.2
95.3
84.6
N.A.
70.8
N.A.
29.1
N.A.
Protein Similarity:
100
99
95.8
77.4
N.A.
92.1
99.8
N.A.
85
38.5
97.8
91.9
N.A.
79.1
N.A.
40.8
N.A.
P-Site Identity:
100
100
0
100
N.A.
80
100
N.A.
6.6
0
100
0
N.A.
86.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
86.6
100
N.A.
13.3
6.6
100
13.3
N.A.
86.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
28
N.A.
27.8
42.7
54.1
Protein Similarity:
N.A.
41.6
N.A.
39.3
59.6
67.2
P-Site Identity:
N.A.
20
N.A.
13.3
6.6
33.3
P-Site Similarity:
N.A.
40
N.A.
20
40
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
13
7
7
13
0
7
0
7
7
0
63
7
7
7
% A
% Cys:
0
0
0
0
7
7
7
13
0
0
7
0
7
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
7
13
0
0
7
0
% D
% Glu:
13
7
0
0
7
7
0
7
0
44
50
0
0
0
19
% E
% Phe:
0
7
0
7
0
7
7
0
57
0
0
0
0
0
7
% F
% Gly:
7
0
0
7
13
0
7
0
19
0
0
13
7
50
0
% G
% His:
0
0
0
44
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
13
7
7
0
0
50
0
0
7
0
0
7
7
7
0
% I
% Lys:
0
0
7
7
38
0
0
7
0
0
13
0
44
7
0
% K
% Leu:
7
0
7
0
0
13
0
0
0
7
0
0
7
0
44
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
13
% M
% Asn:
0
0
13
13
0
7
0
7
0
13
13
0
7
7
0
% N
% Pro:
0
57
13
0
7
0
0
7
0
7
0
0
0
7
7
% P
% Gln:
0
7
32
0
0
0
0
0
7
0
0
0
0
7
0
% Q
% Arg:
7
0
7
7
7
0
7
7
0
7
0
13
7
0
0
% R
% Ser:
50
0
13
0
0
0
19
57
0
0
0
0
0
7
0
% S
% Thr:
0
7
0
0
7
0
38
0
0
0
0
0
7
0
0
% T
% Val:
0
0
0
7
0
7
0
0
0
7
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
7
7
0
7
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _