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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CA
All Species:
22.73
Human Site:
S59
Identified Species:
33.33
UniProt:
Q08209
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08209
NP_000935.1
521
58688
S59
K
E
G
R
L
E
E
S
V
A
L
R
I
I
T
Chimpanzee
Pan troglodytes
XP_001168163
525
58994
S59
K
E
G
R
L
E
E
S
V
A
L
R
I
I
T
Rhesus Macaque
Macaca mulatta
XP_001108447
533
60397
S59
K
E
G
R
L
E
E
S
V
A
L
R
I
I
T
Dog
Lupus familis
XP_535672
673
74856
S211
K
E
G
R
L
E
E
S
V
A
L
R
I
I
T
Cat
Felis silvestris
Mouse
Mus musculus
P48453
525
59155
E68
K
E
G
R
V
D
E
E
I
A
L
R
I
I
N
Rat
Rattus norvegicus
P63329
521
58625
S59
K
E
G
R
L
E
E
S
V
A
L
R
I
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507011
444
50170
D20
D
I
H
G
Q
F
F
D
L
M
K
L
F
E
V
Chicken
Gallus gallus
P48463
309
35545
Frog
Xenopus laevis
NP_001080813
518
58366
S59
K
E
G
R
L
E
E
S
V
A
L
R
I
I
S
Zebra Danio
Brachydanio rerio
NP_001017856
511
57796
P48
K
E
G
R
V
E
E
P
V
A
L
R
I
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
A125
L
E
G
R
I
E
E
A
P
A
L
K
I
I
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48484
321
36353
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
A113
R
E
G
K
L
S
A
A
Q
A
A
R
I
V
T
Red Bread Mold
Neurospora crassa
Q05681
558
63895
E97
R
E
G
R
L
T
E
E
Q
A
L
W
I
I
R
Conservation
Percent
Protein Identity:
100
98.6
95.8
77.4
N.A.
83.2
99.6
N.A.
84.2
27.2
95.3
84.6
N.A.
70.8
N.A.
29.1
N.A.
Protein Similarity:
100
99
95.8
77.4
N.A.
92.1
99.8
N.A.
85
38.5
97.8
91.9
N.A.
79.1
N.A.
40.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
66.6
100
N.A.
0
0
93.3
73.3
N.A.
60
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
100
N.A.
6.6
0
100
86.6
N.A.
80
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
28
N.A.
27.8
42.7
54.1
Protein Similarity:
N.A.
41.6
N.A.
39.3
59.6
67.2
P-Site Identity:
N.A.
0
N.A.
0
46.6
60
P-Site Similarity:
N.A.
0
N.A.
0
73.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
13
0
69
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% D
% Glu:
0
69
0
0
0
50
63
13
0
0
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
7
7
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
69
7
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
0
0
0
7
0
0
0
69
57
0
% I
% Lys:
50
0
0
7
0
0
0
0
0
0
7
7
0
0
0
% K
% Leu:
7
0
0
0
50
0
0
0
7
0
63
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% N
% Pro:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
13
0
0
0
0
0
7
% Q
% Arg:
13
0
0
63
0
0
0
0
0
0
0
57
0
0
7
% R
% Ser:
0
0
0
0
0
7
0
38
0
0
0
0
0
0
7
% S
% Thr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
38
% T
% Val:
0
0
0
0
13
0
0
0
44
0
0
0
0
13
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _