KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CA
All Species:
23.94
Human Site:
T510
Identified Species:
35.11
UniProt:
Q08209
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08209
NP_000935.1
521
58688
T510
L
T
S
E
T
N
G
T
D
S
N
G
S
N
S
Chimpanzee
Pan troglodytes
XP_001168163
525
58994
T514
L
T
S
E
T
N
G
T
D
S
N
G
S
N
S
Rhesus Macaque
Macaca mulatta
XP_001108447
533
60397
T522
L
T
S
E
T
N
G
T
D
S
N
G
S
N
S
Dog
Lupus familis
XP_535672
673
74856
T662
L
T
S
E
T
N
G
T
D
S
N
G
S
N
S
Cat
Felis silvestris
Mouse
Mus musculus
P48453
525
59155
T514
S
L
N
T
A
H
T
T
E
N
H
G
T
G
N
Rat
Rattus norvegicus
P63329
521
58625
T510
L
A
S
E
T
N
G
T
D
S
N
G
S
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507011
444
50170
D434
S
S
E
T
N
G
T
D
S
N
G
S
N
S
S
Chicken
Gallus gallus
P48463
309
35545
H299
A
P
R
R
G
E
P
H
V
T
R
R
T
P
D
Frog
Xenopus laevis
NP_001080813
518
58366
S505
S
I
N
K
A
I
S
S
E
T
N
G
T
D
S
Zebra Danio
Brachydanio rerio
NP_001017856
511
57796
A499
S
M
G
K
M
N
M
A
E
S
N
G
T
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
Q560
E
D
P
N
Q
H
S
Q
Q
G
G
K
N
G
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
E310
A
T
V
E
N
R
G
E
P
K
K
Q
P
I
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
N306
M
M
G
G
S
T
N
N
K
S
G
F
K
S
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48484
321
36353
K311
Q
I
L
K
P
A
E
K
K
T
K
F
M
M
S
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
Y587
K
N
E
N
K
K
Y
Y
E
K
V
W
Q
K
V
Red Bread Mold
Neurospora crassa
Q05681
558
63895
R537
E
R
A
Q
A
L
E
R
A
T
R
E
A
D
N
Conservation
Percent
Protein Identity:
100
98.6
95.8
77.4
N.A.
83.2
99.6
N.A.
84.2
27.2
95.3
84.6
N.A.
70.8
N.A.
29.1
N.A.
Protein Similarity:
100
99
95.8
77.4
N.A.
92.1
99.8
N.A.
85
38.5
97.8
91.9
N.A.
79.1
N.A.
40.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
13.3
93.3
N.A.
6.6
0
20
26.6
N.A.
0
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
60
93.3
N.A.
33.3
13.3
66.6
53.3
N.A.
20
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
28
N.A.
27.8
42.7
54.1
Protein Similarity:
N.A.
41.6
N.A.
39.3
59.6
67.2
P-Site Identity:
N.A.
6.6
N.A.
6.6
0
0
P-Site Similarity:
N.A.
26.6
N.A.
20
6.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
7
7
0
19
7
0
7
7
0
0
0
7
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
7
32
0
0
0
0
19
13
% D
% Glu:
13
0
13
38
0
7
13
7
25
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
7
% F
% Gly:
0
0
13
7
7
7
38
0
0
7
19
50
0
13
0
% G
% His:
0
0
0
0
0
13
0
7
0
0
7
0
0
0
0
% H
% Ile:
0
13
0
0
0
7
0
0
0
0
0
0
0
7
0
% I
% Lys:
7
0
0
19
7
7
0
7
13
13
13
7
7
7
0
% K
% Leu:
32
7
7
0
0
7
0
0
0
0
0
0
0
0
0
% L
% Met:
7
13
0
0
7
0
7
0
0
0
0
0
7
7
0
% M
% Asn:
0
7
13
13
13
38
7
7
0
13
44
0
13
32
13
% N
% Pro:
0
7
7
0
7
0
7
0
7
0
0
0
7
7
0
% P
% Gln:
7
0
0
7
7
0
0
7
7
0
0
7
7
0
0
% Q
% Arg:
0
7
7
7
0
7
0
7
0
0
13
7
0
0
0
% R
% Ser:
25
7
32
0
7
0
13
7
7
44
0
7
32
13
50
% S
% Thr:
0
32
0
13
32
7
13
38
0
25
0
0
25
0
0
% T
% Val:
0
0
7
0
0
0
0
0
7
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _