KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CA
All Species:
45.15
Human Site:
Y291
Identified Species:
66.22
UniProt:
Q08209
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08209
NP_000935.1
521
58688
Y291
Q
D
A
G
Y
R
M
Y
R
K
S
Q
T
T
G
Chimpanzee
Pan troglodytes
XP_001168163
525
58994
Y295
Q
D
A
G
Y
R
M
Y
R
K
S
Q
T
T
G
Rhesus Macaque
Macaca mulatta
XP_001108447
533
60397
Y313
Q
D
A
G
Y
R
M
Y
R
K
S
Q
T
T
G
Dog
Lupus familis
XP_535672
673
74856
Y443
Q
D
A
G
Y
R
M
Y
R
K
S
Q
T
T
G
Cat
Felis silvestris
Mouse
Mus musculus
P48453
525
59155
Y300
Q
D
A
G
Y
R
M
Y
R
K
S
Q
T
T
G
Rat
Rattus norvegicus
P63329
521
58625
Y291
Q
D
A
G
Y
R
M
Y
R
K
S
Q
T
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507011
444
50170
A231
S
L
I
T
I
F
S
A
P
N
Y
L
D
V
Y
Chicken
Gallus gallus
P48463
309
35545
T96
R
G
Y
Y
S
V
E
T
V
T
L
L
V
A
L
Frog
Xenopus laevis
NP_001080813
518
58366
Y291
Q
D
A
G
Y
R
M
Y
R
K
S
Q
T
T
G
Zebra Danio
Brachydanio rerio
NP_001017856
511
57796
Y280
Q
D
A
G
Y
R
M
Y
R
K
S
Q
T
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
Y357
Q
D
A
G
Y
R
M
Y
R
K
S
Q
T
T
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
L107
S
V
E
T
F
I
L
L
M
L
L
K
C
R
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
C102
K
Q
S
L
E
T
I
C
L
L
L
A
Y
K
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48484
321
36353
G107
L
G
D
Y
V
D
R
G
K
Q
S
L
E
T
I
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
Y369
Q
D
A
G
Y
R
M
Y
K
N
T
K
T
L
G
Red Bread Mold
Neurospora crassa
Q05681
558
63895
Y329
Q
D
A
G
Y
R
M
Y
R
K
T
R
T
T
G
Conservation
Percent
Protein Identity:
100
98.6
95.8
77.4
N.A.
83.2
99.6
N.A.
84.2
27.2
95.3
84.6
N.A.
70.8
N.A.
29.1
N.A.
Protein Similarity:
100
99
95.8
77.4
N.A.
92.1
99.8
N.A.
85
38.5
97.8
91.9
N.A.
79.1
N.A.
40.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
0
100
100
N.A.
100
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
6.6
100
100
N.A.
100
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
28
N.A.
27.8
42.7
54.1
Protein Similarity:
N.A.
41.6
N.A.
39.3
59.6
67.2
P-Site Identity:
N.A.
0
N.A.
13.3
66.6
86.6
P-Site Similarity:
N.A.
20
N.A.
26.6
86.6
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
69
0
0
0
0
7
0
0
0
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% C
% Asp:
0
69
7
0
0
7
0
0
0
0
0
0
7
0
0
% D
% Glu:
0
0
7
0
7
0
7
0
0
0
0
0
7
0
0
% E
% Phe:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
69
0
0
0
7
0
0
0
0
0
0
69
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
7
7
7
0
0
0
0
0
0
0
7
% I
% Lys:
7
0
0
0
0
0
0
0
13
63
0
13
0
7
0
% K
% Leu:
7
7
0
7
0
0
7
7
7
13
19
19
0
7
7
% L
% Met:
0
0
0
0
0
0
69
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
69
7
0
0
0
0
0
0
0
7
0
57
0
0
0
% Q
% Arg:
7
0
0
0
0
69
7
0
63
0
0
7
0
7
0
% R
% Ser:
13
0
7
0
7
0
7
0
0
0
63
0
0
0
0
% S
% Thr:
0
0
0
13
0
7
0
7
0
7
13
0
69
69
0
% T
% Val:
0
7
0
0
7
7
0
0
7
0
0
0
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
13
69
0
0
69
0
0
7
0
7
0
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _