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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP3CA
All Species:
46.97
Human Site:
Y315
Identified Species:
68.89
UniProt:
Q08209
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08209
NP_000935.1
521
58688
Y315
A
P
N
Y
L
D
V
Y
N
N
K
A
A
V
L
Chimpanzee
Pan troglodytes
XP_001168163
525
58994
Y319
A
P
N
Y
L
D
V
Y
N
N
K
A
A
V
L
Rhesus Macaque
Macaca mulatta
XP_001108447
533
60397
Y337
A
P
N
Y
L
D
V
Y
N
N
K
A
A
V
L
Dog
Lupus familis
XP_535672
673
74856
Y467
A
P
N
Y
L
D
V
Y
N
N
K
A
A
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P48453
525
59155
Y324
A
P
N
Y
L
D
V
Y
N
N
K
A
A
V
L
Rat
Rattus norvegicus
P63329
521
58625
Y315
A
P
N
Y
L
D
V
Y
N
N
K
A
A
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507011
444
50170
R255
E
N
N
V
M
N
I
R
Q
F
N
C
S
P
H
Chicken
Gallus gallus
P48463
309
35545
S120
I
L
R
G
N
H
E
S
R
Q
I
T
Q
V
Y
Frog
Xenopus laevis
NP_001080813
518
58366
Y315
A
P
N
Y
L
D
V
Y
N
N
K
A
A
V
L
Zebra Danio
Brachydanio rerio
NP_001017856
511
57796
Y304
A
P
N
Y
L
D
V
Y
N
N
K
A
A
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27889
570
63082
Y381
A
P
N
Y
L
D
V
Y
N
N
K
A
A
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTT8
321
36288
T131
N
H
E
S
R
Q
I
T
Q
V
Y
G
F
Y
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
S126
R
G
N
H
E
C
A
S
V
N
R
I
Y
G
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48484
321
36353
L131
Y
P
G
N
F
F
L
L
R
G
N
H
E
C
A
Baker's Yeast
Sacchar. cerevisiae
P14747
604
68509
Y393
A
P
N
Y
L
D
T
Y
N
N
K
A
A
I
L
Red Bread Mold
Neurospora crassa
Q05681
558
63895
Y353
A
P
N
Y
L
D
V
Y
N
N
K
A
A
V
L
Conservation
Percent
Protein Identity:
100
98.6
95.8
77.4
N.A.
83.2
99.6
N.A.
84.2
27.2
95.3
84.6
N.A.
70.8
N.A.
29.1
N.A.
Protein Similarity:
100
99
95.8
77.4
N.A.
92.1
99.8
N.A.
85
38.5
97.8
91.9
N.A.
79.1
N.A.
40.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
6.6
100
100
N.A.
100
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
6.6
100
100
N.A.
100
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
28
N.A.
27.8
42.7
54.1
Protein Similarity:
N.A.
41.6
N.A.
39.3
59.6
67.2
P-Site Identity:
N.A.
13.3
N.A.
6.6
86.6
100
P-Site Similarity:
N.A.
26.6
N.A.
13.3
93.3
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
69
0
0
0
0
0
7
0
0
0
0
69
69
0
7
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
7
0
7
0
% C
% Asp:
0
0
0
0
0
69
0
0
0
0
0
0
0
0
7
% D
% Glu:
7
0
7
0
7
0
7
0
0
0
0
0
7
0
0
% E
% Phe:
0
0
0
0
7
7
0
0
0
7
0
0
7
0
7
% F
% Gly:
0
7
7
7
0
0
0
0
0
7
0
7
0
7
0
% G
% His:
0
7
0
7
0
7
0
0
0
0
0
7
0
0
7
% H
% Ile:
7
0
0
0
0
0
13
0
0
0
7
7
0
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
69
0
0
0
0
% K
% Leu:
0
7
0
0
69
0
7
7
0
0
0
0
0
0
69
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
82
7
7
7
0
0
69
75
13
0
0
0
0
% N
% Pro:
0
75
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
7
0
0
13
7
0
0
7
0
0
% Q
% Arg:
7
0
7
0
7
0
0
7
13
0
7
0
0
0
0
% R
% Ser:
0
0
0
7
0
0
0
13
0
0
0
0
7
0
0
% S
% Thr:
0
0
0
0
0
0
7
7
0
0
0
7
0
0
0
% T
% Val:
0
0
0
7
0
0
63
0
7
7
0
0
0
69
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
69
0
0
0
69
0
0
7
0
7
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _