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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX9
All Species:
26.06
Human Site:
Y218
Identified Species:
52.12
UniProt:
Q08211
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08211
NP_001348.2
1270
140958
Y218
F
I
A
E
M
T
I
Y
I
K
Q
L
G
R
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001114384
1275
141297
Y218
F
I
A
E
M
T
I
Y
I
K
Q
L
G
R
R
Dog
Lupus familis
XP_849581
1276
141244
Y219
F
I
A
E
M
T
I
Y
I
K
Q
L
G
R
R
Cat
Felis silvestris
Mouse
Mus musculus
O70133
1380
149456
Y220
F
I
A
E
M
T
I
Y
I
K
Q
L
G
R
R
Rat
Rattus norvegicus
Q5BJS0
1194
133979
M210
D
V
T
E
F
L
S
M
T
Q
Q
D
S
H
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515991
1325
145204
Y223
F
I
A
E
M
T
V
Y
V
K
Q
L
G
R
R
Chicken
Gallus gallus
Q5ZI74
1231
137685
A221
E
Q
G
R
M
P
K
A
M
R
R
E
E
L
E
Frog
Xenopus laevis
Q68FK8
1262
140510
Y221
F
I
A
E
M
T
L
Y
V
K
Q
L
G
R
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24785
1293
143643
Y207
F
L
A
E
L
S
I
Y
V
P
A
L
N
R
T
Honey Bee
Apis mellifera
XP_396525
1239
139006
K217
G
R
E
T
G
S
N
K
Q
T
A
S
K
S
C
Nematode Worm
Caenorhab. elegans
Q22307
1301
144195
F210
M
E
T
T
A
Q
I
F
V
P
Q
I
N
K
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06698
1435
163026
V262
L
V
R
F
P
K
K
V
W
E
N
S
I
F
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.2
94.1
N.A.
84.7
27.5
N.A.
85.5
27.3
79
N.A.
N.A.
50.5
55.2
42.7
N.A.
Protein Similarity:
100
N.A.
99.2
96.1
N.A.
88.2
44.1
N.A.
89.5
45.1
90.1
N.A.
N.A.
69.3
71.2
62.5
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
86.6
6.6
80
N.A.
N.A.
46.6
0
13.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
26.6
N.A.
100
26.6
100
N.A.
N.A.
73.3
6.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
59
0
9
0
0
9
0
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
9
9
9
67
0
0
0
0
0
9
0
9
9
0
9
% E
% Phe:
59
0
0
9
9
0
0
9
0
0
0
0
0
9
0
% F
% Gly:
9
0
9
0
9
0
0
0
0
0
0
0
50
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
50
0
0
0
0
50
0
34
0
0
9
9
0
0
% I
% Lys:
0
0
0
0
0
9
17
9
0
50
0
0
9
9
9
% K
% Leu:
9
9
0
0
9
9
9
0
0
0
0
59
0
9
0
% L
% Met:
9
0
0
0
59
0
0
9
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
9
0
17
0
17
% N
% Pro:
0
0
0
0
9
9
0
0
0
17
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
9
0
0
9
9
67
0
0
0
0
% Q
% Arg:
0
9
9
9
0
0
0
0
0
9
9
0
0
59
42
% R
% Ser:
0
0
0
0
0
17
9
0
0
0
0
17
9
9
0
% S
% Thr:
0
0
17
17
0
50
0
0
9
9
0
0
0
0
9
% T
% Val:
0
17
0
0
0
0
9
9
34
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _