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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IL10RB All Species: 13.94
Human Site: Y254 Identified Species: 30.67
UniProt: Q08334 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08334 NP_000619.3 325 36995 Y254 C V Y K K T K Y A F S P R N S
Chimpanzee Pan troglodytes XP_531433 325 36916 Y254 C V Y K K T K Y A F S P R N S
Rhesus Macaque Macaca mulatta XP_001094340 456 50541 Y350 C I Y K K T K Y T F S P G N S
Dog Lupus familis XP_535581 374 41888 H253 C L Y K R T K H V F S P R N C
Cat Felis silvestris
Mouse Mus musculus Q61190 349 39755 H254 L I Y K K T K H T F R S G T S
Rat Rattus norvegicus NP_001100581 351 40237 Y256 F I Y K K T K Y T F H S G T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514079 463 50722 Y375 Y L Y R Q A R Y V F F P G Y S
Chicken Gallus gallus NP_990188 341 39044 H258 Y L Y R F T K H V F F P S Y I
Frog Xenopus laevis NP_001087014 305 34349 P236 L I P L C L S P V I I V G L F
Zebra Danio Brachydanio rerio NP_001077337 313 35824 F244 L V A V L L I F M A V W Y S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P92029 217 24761 A148 Q V A V V L M A L G F V G A L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 59.8 69.2 N.A. 65 67.8 N.A. 34.1 40.7 32.3 26.4 N.A. 20 N.A. N.A. N.A.
Protein Similarity: 100 99.6 64 76.4 N.A. 76.5 76.9 N.A. 46.2 58.9 50.4 47 N.A. 34.7 N.A. N.A. N.A.
P-Site Identity: 100 100 80 66.6 N.A. 46.6 53.3 N.A. 33.3 33.3 0 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 86.6 N.A. 60 60 N.A. 60 53.3 6.6 20 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 0 0 10 0 10 19 10 0 0 0 10 0 % A
% Cys: 37 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 10 0 0 10 0 73 28 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 0 55 0 0 % G
% His: 0 0 0 0 0 0 0 28 0 0 10 0 0 0 0 % H
% Ile: 0 37 0 0 0 0 10 0 0 10 10 0 0 0 10 % I
% Lys: 0 0 0 55 46 0 64 0 0 0 0 0 0 0 0 % K
% Leu: 28 28 0 10 10 28 0 0 10 0 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 37 0 % N
% Pro: 0 0 10 0 0 0 0 10 0 0 0 55 0 0 0 % P
% Gln: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 19 10 0 10 0 0 0 10 0 28 0 0 % R
% Ser: 0 0 0 0 0 0 10 0 0 0 37 19 10 10 55 % S
% Thr: 0 0 0 0 0 64 0 0 28 0 0 0 0 19 0 % T
% Val: 0 37 0 19 10 0 0 0 37 0 10 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 19 0 73 0 0 0 0 46 0 0 0 0 10 19 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _