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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDR1 All Species: 22.12
Human Site: S496 Identified Species: 40.56
UniProt: Q08345 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08345 NP_001945.3 913 101128 S496 P R G N P P H S A P C V P N G
Chimpanzee Pan troglodytes Q7YR43 909 100624 S492 P R G N P P H S A P C V P N G
Rhesus Macaque Macaca mulatta NP_001108424 875 97033 S495 P R G N P P H S A P C V P N G
Dog Lupus familis XP_532062 920 101679 S503 P R G N P P H S A P S V P N G
Cat Felis silvestris
Mouse Mus musculus Q03146 911 101142 S494 P R G T P P H S A P C V P N G
Rat Rattus norvegicus Q63474 910 101146 S493 P R G T P T H S A P C V P N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515915 914 101965 V491 M L D D E M T V S L S L P S E
Chicken Gallus gallus Q91987 818 91718 T428 K E N E D S I T V Y V V V G I
Frog Xenopus laevis NP_001083540 945 106089 G521 E R I I T S D G E Y Q E P S H
Zebra Danio Brachydanio rerio XP_684261 892 101731 A476 M L D D E L T A S L S I Q S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24488 685 78124 I330 A A I I L I F I I I F A I I L
Honey Bee Apis mellifera XP_394687 882 100064 L472 Y A T T T P Q L H K T I T D Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202828 913 103393 F475 H R L P T L A F E A N C N G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 95.2 95.1 N.A. 93.6 93.7 N.A. 53.5 24.5 60.6 52.2 N.A. 23.5 34.3 N.A. 39.1
Protein Similarity: 100 99.5 95.5 96.6 N.A. 95.8 95.9 N.A. 65.8 41.5 72.3 65.7 N.A. 40.3 50.5 N.A. 54.4
P-Site Identity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. 6.6 6.6 13.3 0 N.A. 0 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. 33.3 13.3 20 33.3 N.A. 0 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 0 0 0 0 8 8 47 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 39 8 0 0 0 % C
% Asp: 0 0 16 16 8 0 8 0 0 0 0 0 0 8 0 % D
% Glu: 8 8 0 8 16 0 0 0 16 0 0 8 0 0 16 % E
% Phe: 0 0 0 0 0 0 8 8 0 0 8 0 0 0 0 % F
% Gly: 0 0 47 0 0 0 0 8 0 0 0 0 0 16 54 % G
% His: 8 0 0 0 0 0 47 0 8 0 0 0 0 0 8 % H
% Ile: 0 0 16 16 0 8 8 8 8 8 0 16 8 8 8 % I
% Lys: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 0 16 8 0 8 16 0 8 0 16 0 8 0 0 8 % L
% Met: 16 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 31 0 0 0 0 0 0 8 0 8 47 0 % N
% Pro: 47 0 0 8 47 47 0 0 0 47 0 0 62 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 8 0 8 0 0 % Q
% Arg: 0 62 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 16 0 47 16 0 24 0 0 24 0 % S
% Thr: 0 0 8 24 24 8 16 8 0 0 8 0 8 0 0 % T
% Val: 0 0 0 0 0 0 0 8 8 0 8 54 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 16 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _