KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDR1
All Species:
26.36
Human Site:
T469
Identified Species:
48.33
UniProt:
Q08345
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08345
NP_001945.3
913
101128
T469
H
L
S
V
P
G
D
T
I
L
I
N
N
R
P
Chimpanzee
Pan troglodytes
Q7YR43
909
100624
T465
H
L
S
V
P
G
D
T
I
L
I
N
N
R
P
Rhesus Macaque
Macaca mulatta
NP_001108424
875
97033
T468
H
L
S
V
P
G
D
T
I
L
I
N
N
R
P
Dog
Lupus familis
XP_532062
920
101679
T476
H
L
S
V
P
G
D
T
I
L
I
N
N
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q03146
911
101142
T467
H
L
S
V
P
G
D
T
I
L
I
N
N
R
P
Rat
Rattus norvegicus
Q63474
910
101146
T466
H
L
S
V
P
G
D
T
I
L
I
N
N
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515915
914
101965
I464
I
F
I
L
V
A
I
I
V
I
I
L
W
R
Q
Chicken
Gallus gallus
Q91987
818
91718
N401
Y
E
Y
E
T
T
P
N
D
L
G
D
T
T
N
Frog
Xenopus laevis
NP_001083540
945
106089
T494
H
L
S
L
P
T
D
T
V
V
I
N
N
T
H
Zebra Danio
Brachydanio rerio
XP_684261
892
101731
I449
I
F
I
L
V
A
I
I
V
I
I
L
W
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24488
685
78124
E303
S
S
R
E
R
I
I
E
L
C
D
I
P
K
C
Honey Bee
Apis mellifera
XP_394687
882
100064
E445
L
K
V
S
V
Q
E
E
G
E
D
K
G
P
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202828
913
103393
L448
V
V
T
V
L
L
L
L
V
L
L
F
A
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.2
95.1
N.A.
93.6
93.7
N.A.
53.5
24.5
60.6
52.2
N.A.
23.5
34.3
N.A.
39.1
Protein Similarity:
100
99.5
95.5
96.6
N.A.
95.8
95.9
N.A.
65.8
41.5
72.3
65.7
N.A.
40.3
50.5
N.A.
54.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
6.6
60
13.3
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
20
80
33.3
N.A.
13.3
6.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
54
0
8
0
16
8
0
0
0
% D
% Glu:
0
8
0
16
0
0
8
16
0
8
0
0
0
0
0
% E
% Phe:
0
16
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
47
0
0
8
0
8
0
8
0
0
% G
% His:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
16
0
16
0
0
8
24
16
47
16
70
8
0
0
8
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% K
% Leu:
8
54
0
24
8
8
8
8
8
62
8
16
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
54
54
0
8
% N
% Pro:
0
0
0
0
54
0
8
0
0
0
0
0
8
8
47
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
16
% Q
% Arg:
0
0
8
0
8
0
0
0
0
0
0
0
0
62
0
% R
% Ser:
8
8
54
8
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
8
16
0
54
0
0
0
0
8
16
0
% T
% Val:
8
8
8
54
24
0
0
0
31
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% W
% Tyr:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _