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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDR1
All Species:
24.85
Human Site:
Y484
Identified Species:
45.56
UniProt:
Q08345
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08345
NP_001945.3
913
101128
Y484
G
P
R
E
P
P
P
Y
Q
E
P
R
P
R
G
Chimpanzee
Pan troglodytes
Q7YR43
909
100624
Y480
G
P
R
E
P
P
P
Y
Q
E
P
R
P
R
G
Rhesus Macaque
Macaca mulatta
NP_001108424
875
97033
Y483
G
P
R
E
P
P
P
Y
Q
E
P
R
P
R
G
Dog
Lupus familis
XP_532062
920
101679
Y491
G
P
L
E
P
P
P
Y
Q
E
P
R
P
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q03146
911
101142
Y482
G
P
R
E
P
P
P
Y
Q
E
P
R
P
R
G
Rat
Rattus norvegicus
Q63474
910
101146
Y481
G
P
R
E
P
P
P
Y
Q
E
P
R
P
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515915
914
101965
K479
F
W
Q
K
M
L
E
K
A
S
R
R
M
L
D
Chicken
Gallus gallus
Q91987
818
91718
P416
N
S
N
Q
I
T
S
P
D
V
S
N
K
E
N
Frog
Xenopus laevis
NP_001083540
945
106089
H509
N
A
P
G
P
P
R
H
A
N
R
Y
E
R
I
Zebra Danio
Brachydanio rerio
XP_684261
892
101731
K464
V
W
Q
K
M
L
E
K
V
S
R
R
M
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24488
685
78124
I318
A
D
K
I
W
I
A
I
V
G
T
T
A
A
I
Honey Bee
Apis mellifera
XP_394687
882
100064
Y460
C
P
P
L
P
A
Q
Y
Q
P
A
A
Y
A
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202828
913
103393
Y463
L
F
L
Y
R
R
K
Y
I
K
L
K
H
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.2
95.1
N.A.
93.6
93.7
N.A.
53.5
24.5
60.6
52.2
N.A.
23.5
34.3
N.A.
39.1
Protein Similarity:
100
99.5
95.5
96.6
N.A.
95.8
95.9
N.A.
65.8
41.5
72.3
65.7
N.A.
40.3
50.5
N.A.
54.4
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
0
20
6.6
N.A.
0
26.6
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
20
6.6
26.6
20
N.A.
6.6
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
8
0
16
0
8
8
8
16
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
16
% D
% Glu:
0
0
0
47
0
0
16
0
0
47
0
0
8
8
0
% E
% Phe:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
47
0
0
8
0
0
0
0
0
8
0
0
0
0
47
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
8
8
8
0
8
8
0
0
0
0
0
16
% I
% Lys:
0
0
8
16
0
0
8
16
0
8
0
8
8
0
0
% K
% Leu:
8
0
16
8
0
16
0
0
0
0
8
0
0
16
8
% L
% Met:
0
0
0
0
16
0
0
0
0
0
0
0
16
0
0
% M
% Asn:
16
0
8
0
0
0
0
0
0
8
0
8
0
0
8
% N
% Pro:
0
54
16
0
62
54
47
8
0
8
47
0
47
0
0
% P
% Gln:
0
0
16
8
0
0
8
0
54
0
0
0
0
0
0
% Q
% Arg:
0
0
39
0
8
8
8
0
0
0
24
62
0
62
0
% R
% Ser:
0
8
0
0
0
0
8
0
0
16
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
8
% T
% Val:
8
0
0
0
0
0
0
0
16
8
0
0
0
0
0
% V
% Trp:
0
16
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
62
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _