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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDR1
All Species:
31.82
Human Site:
Y881
Identified Species:
58.33
UniProt:
Q08345
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08345
NP_001945.3
913
101128
Y881
P
A
C
P
Q
G
L
Y
E
L
M
L
R
C
W
Chimpanzee
Pan troglodytes
Q7YR43
909
100624
Y877
P
A
C
P
Q
G
L
Y
E
L
M
L
R
C
W
Rhesus Macaque
Macaca mulatta
NP_001108424
875
97033
Y843
P
A
C
P
Q
G
L
Y
E
L
M
L
R
C
W
Dog
Lupus familis
XP_532062
920
101679
Y888
P
S
C
P
L
G
L
Y
E
L
M
L
R
C
W
Cat
Felis silvestris
Mouse
Mus musculus
Q03146
911
101142
Y879
P
A
C
P
Q
T
L
Y
E
L
M
L
R
C
W
Rat
Rattus norvegicus
Q63474
910
101146
Y878
P
A
C
P
Q
T
L
Y
E
L
M
L
R
C
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515915
914
101965
Y883
A
I
C
P
D
P
V
Y
K
L
M
L
S
C
W
Chicken
Gallus gallus
Q91987
818
91718
L783
K
E
V
Y
D
L
M
L
G
C
W
Q
R
E
P
Frog
Xenopus laevis
NP_001083540
945
106089
Y907
P
P
C
P
Q
P
L
Y
E
L
M
L
Q
C
W
Zebra Danio
Brachydanio rerio
XP_684261
892
101731
P859
L
P
Q
P
P
M
C
P
D
P
V
Y
K
L
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24488
685
78124
H654
S
L
M
I
E
C
W
H
E
Q
S
V
K
R
P
Honey Bee
Apis mellifera
XP_394687
882
100064
Y842
K
N
C
P
K
D
I
Y
E
L
M
R
E
C
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202828
913
103393
H876
P
Q
C
P
K
D
I
H
N
L
M
K
R
C
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.2
95.1
N.A.
93.6
93.7
N.A.
53.5
24.5
60.6
52.2
N.A.
23.5
34.3
N.A.
39.1
Protein Similarity:
100
99.5
95.5
96.6
N.A.
95.8
95.9
N.A.
65.8
41.5
72.3
65.7
N.A.
40.3
50.5
N.A.
54.4
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
53.3
6.6
80
6.6
N.A.
6.6
53.3
N.A.
53.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
66.6
13.3
86.6
26.6
N.A.
33.3
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
39
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
77
0
0
8
8
0
0
8
0
0
0
77
0
% C
% Asp:
0
0
0
0
16
16
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
8
0
0
0
70
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
31
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
0
16
0
0
0
0
0
0
0
0
% I
% Lys:
16
0
0
0
16
0
0
0
8
0
0
8
16
0
0
% K
% Leu:
8
8
0
0
8
8
54
8
0
77
0
62
0
8
0
% L
% Met:
0
0
8
0
0
8
8
0
0
0
77
0
0
0
8
% M
% Asn:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
62
16
0
85
8
16
0
8
0
8
0
0
0
0
16
% P
% Gln:
0
8
8
0
47
0
0
0
0
8
0
8
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
62
8
0
% R
% Ser:
8
8
0
0
0
0
0
0
0
0
8
0
8
0
0
% S
% Thr:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
8
0
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
77
% W
% Tyr:
0
0
0
8
0
0
0
70
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _