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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY2
All Species:
15.15
Human Site:
S718
Identified Species:
30.3
UniProt:
Q08462
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08462
NP_065433.2
1091
123603
S718
T
A
N
T
T
N
T
S
F
S
A
S
N
N
Q
Chimpanzee
Pan troglodytes
XP_509874
1077
119824
I702
A
P
N
V
S
S
M
I
S
N
L
S
W
E
L
Rhesus Macaque
Macaca mulatta
XP_001083524
1091
123478
S718
T
A
N
T
T
N
T
S
F
S
A
S
N
N
Q
Dog
Lupus familis
XP_535798
1051
118761
S678
T
A
N
T
S
N
M
S
L
S
A
L
S
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80TL1
1090
123251
N717
T
A
N
A
S
N
A
N
V
S
V
P
D
N
Q
Rat
Rattus norvegicus
P26769
1090
123297
N717
T
A
N
T
S
N
A
N
V
S
V
P
D
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519046
1069
121143
S697
S
L
N
T
S
N
S
S
F
P
D
I
N
D
E
Chicken
Gallus gallus
Q9DGG6
1334
149273
L840
C
T
K
R
L
L
E
L
I
S
G
W
L
P
R
Frog
Xenopus laevis
P98999
1305
145393
V818
L
A
L
V
L
L
S
V
C
G
L
L
G
F
L
Zebra Danio
Brachydanio rerio
NP_001093457
1139
128958
S762
S
L
N
I
S
N
S
S
M
D
G
P
Y
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW60
1307
142798
S944
I
L
E
S
N
F
S
S
V
F
V
N
S
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780688
889
100312
A560
Q
V
G
V
S
V
K
A
F
I
M
I
L
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.3
99.2
93.3
N.A.
94.4
94.5
N.A.
86.8
26.7
27.5
75.3
N.A.
34.6
N.A.
N.A.
39.4
Protein Similarity:
100
71
99.7
94.9
N.A.
96.4
96.6
N.A.
91.9
44
44.7
84.1
N.A.
51.1
N.A.
N.A.
53.3
P-Site Identity:
100
13.3
100
66.6
N.A.
46.6
53.3
N.A.
40
6.6
6.6
26.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
100
80
N.A.
66.6
73.3
N.A.
73.3
13.3
13.3
46.6
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
50
0
9
0
0
17
9
0
0
25
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
9
0
17
9
0
% D
% Glu:
0
0
9
0
0
0
9
0
0
0
0
0
0
9
9
% E
% Phe:
0
0
0
0
0
9
0
0
34
9
0
0
0
9
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
9
17
0
9
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
9
0
0
0
9
9
9
0
17
0
0
0
% I
% Lys:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
9
25
9
0
17
17
0
9
9
0
17
17
17
0
34
% L
% Met:
0
0
0
0
0
0
17
0
9
0
9
0
0
0
0
% M
% Asn:
0
0
67
0
9
59
0
17
0
9
0
9
25
42
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
9
0
25
0
9
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
17
0
0
9
59
9
34
50
9
50
0
25
17
0
0
% S
% Thr:
42
9
0
42
17
0
17
0
0
0
0
0
0
9
0
% T
% Val:
0
9
0
25
0
9
0
9
25
0
25
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _