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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY2
All Species:
24.55
Human Site:
T526
Identified Species:
49.09
UniProt:
Q08462
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08462
NP_065433.2
1091
123603
T526
E
N
G
K
I
S
T
T
D
V
P
M
G
Q
H
Chimpanzee
Pan troglodytes
XP_509874
1077
119824
K510
T
S
T
P
L
P
E
K
T
L
A
S
F
S
T
Rhesus Macaque
Macaca mulatta
XP_001083524
1091
123478
T526
E
N
G
K
I
S
T
T
D
V
P
M
G
Q
H
Dog
Lupus familis
XP_535798
1051
118761
T486
E
N
G
K
I
S
T
T
D
V
P
M
G
Q
H
Cat
Felis silvestris
Mouse
Mus musculus
Q80TL1
1090
123251
T525
E
N
G
K
I
S
T
T
D
V
P
M
G
Q
H
Rat
Rattus norvegicus
P26769
1090
123297
T525
E
N
G
K
I
S
T
T
D
V
P
M
G
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519046
1069
121143
T505
E
N
G
K
I
S
T
T
D
V
P
M
G
Q
H
Chicken
Gallus gallus
Q9DGG6
1334
149273
L619
C
P
S
C
S
T
T
L
V
P
P
C
D
V
S
Frog
Xenopus laevis
P98999
1305
145393
S624
E
T
L
K
S
C
P
S
C
G
E
T
A
A
R
Zebra Danio
Brachydanio rerio
NP_001093457
1139
128958
R573
E
N
G
M
I
N
T
R
D
V
P
L
G
Q
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW60
1307
142798
L567
I
N
S
Q
E
A
P
L
H
A
P
L
A
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780688
889
100312
S396
V
F
A
C
L
V
I
S
Q
L
L
T
Q
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.3
99.2
93.3
N.A.
94.4
94.5
N.A.
86.8
26.7
27.5
75.3
N.A.
34.6
N.A.
N.A.
39.4
Protein Similarity:
100
71
99.7
94.9
N.A.
96.4
96.6
N.A.
91.9
44
44.7
84.1
N.A.
51.1
N.A.
N.A.
53.3
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
100
13.3
13.3
66.6
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
20
20
86.6
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
0
0
0
9
9
0
17
9
9
% A
% Cys:
9
0
0
17
0
9
0
0
9
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
59
0
0
0
9
0
0
% D
% Glu:
67
0
0
0
9
0
9
0
0
0
9
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
59
0
0
0
0
0
0
9
0
0
59
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
50
% H
% Ile:
9
0
0
0
59
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
59
0
0
0
9
0
0
0
0
0
0
9
% K
% Leu:
0
0
9
0
17
0
0
17
0
17
9
17
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
50
0
0
0
% M
% Asn:
0
67
0
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
9
0
9
17
0
0
9
75
0
0
9
0
% P
% Gln:
0
0
0
9
0
0
0
0
9
0
0
0
9
59
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% R
% Ser:
0
9
17
0
17
50
0
17
0
0
0
9
0
17
9
% S
% Thr:
9
9
9
0
0
9
67
50
9
0
0
17
0
0
9
% T
% Val:
9
0
0
0
0
9
0
0
9
59
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _