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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY2
All Species:
22.12
Human Site:
T804
Identified Species:
44.24
UniProt:
Q08462
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08462
NP_065433.2
1091
123603
T804
G
I
W
K
D
L
K
T
M
G
S
V
S
L
S
Chimpanzee
Pan troglodytes
XP_509874
1077
119824
L790
G
V
L
K
E
P
K
L
M
G
A
I
S
F
F
Rhesus Macaque
Macaca mulatta
XP_001083524
1091
123478
T804
G
I
W
K
D
L
K
T
M
G
S
V
S
L
S
Dog
Lupus familis
XP_535798
1051
118761
T764
G
I
W
K
D
L
K
T
M
G
S
V
S
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q80TL1
1090
123251
T803
G
I
W
K
D
L
K
T
M
G
S
V
S
L
S
Rat
Rattus norvegicus
P26769
1090
123297
T803
G
I
W
K
D
L
K
T
M
G
S
V
S
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519046
1069
121143
T782
G
I
W
K
D
L
K
T
M
G
S
V
S
L
F
Chicken
Gallus gallus
Q9DGG6
1334
149273
P944
N
L
S
S
R
K
S
P
C
N
S
S
M
P
A
Frog
Xenopus laevis
P98999
1305
145393
F904
P
M
V
Q
Y
C
N
F
C
Q
L
S
S
S
A
Zebra Danio
Brachydanio rerio
NP_001093457
1139
128958
L847
Q
P
D
R
P
G
V
L
K
D
L
K
T
M
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW60
1307
142798
L1033
L
E
I
K
G
F
L
L
L
L
V
I
I
L
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780688
889
100312
V644
Y
R
V
E
R
E
E
V
E
T
M
E
S
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.3
99.2
93.3
N.A.
94.4
94.5
N.A.
86.8
26.7
27.5
75.3
N.A.
34.6
N.A.
N.A.
39.4
Protein Similarity:
100
71
99.7
94.9
N.A.
96.4
96.6
N.A.
91.9
44
44.7
84.1
N.A.
51.1
N.A.
N.A.
53.3
P-Site Identity:
100
40
100
93.3
N.A.
100
100
N.A.
93.3
6.6
6.6
0
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
66.6
100
93.3
N.A.
100
100
N.A.
93.3
20
26.6
20
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
17
% A
% Cys:
0
0
0
0
0
9
0
0
17
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
50
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
9
0
9
9
9
9
0
9
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
9
0
0
0
0
0
9
25
% F
% Gly:
59
0
0
0
9
9
0
0
0
59
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
50
9
0
0
0
0
0
0
0
0
17
9
0
0
% I
% Lys:
0
0
0
67
0
9
59
0
9
0
0
9
0
0
0
% K
% Leu:
9
9
9
0
0
50
9
25
9
9
17
0
0
67
0
% L
% Met:
0
9
0
0
0
0
0
0
59
0
9
0
9
9
0
% M
% Asn:
9
0
0
0
0
0
9
0
0
9
0
0
0
0
9
% N
% Pro:
9
9
0
0
9
9
0
9
0
0
0
0
0
9
0
% P
% Gln:
9
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
9
0
9
17
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
9
0
0
9
0
0
0
59
17
75
9
34
% S
% Thr:
0
0
0
0
0
0
0
50
0
9
0
0
9
0
0
% T
% Val:
0
9
17
0
0
0
9
9
0
0
9
50
0
0
9
% V
% Trp:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _