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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY2
All Species:
20.91
Human Site:
Y452
Identified Species:
41.82
UniProt:
Q08462
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08462
NP_065433.2
1091
123603
Y452
D
G
D
I
R
D
P
Y
L
K
Q
H
L
V
K
Chimpanzee
Pan troglodytes
XP_509874
1077
119824
L436
M
E
H
R
D
P
Y
L
R
E
L
G
E
P
T
Rhesus Macaque
Macaca mulatta
XP_001083524
1091
123478
Y452
D
G
D
I
R
D
P
Y
L
K
Q
H
L
V
K
Dog
Lupus familis
XP_535798
1051
118761
P412
G
D
G
D
I
R
D
P
Y
L
K
Q
H
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80TL1
1090
123251
Y451
D
G
E
I
R
D
P
Y
L
K
Q
H
L
V
K
Rat
Rattus norvegicus
P26769
1090
123297
Y451
D
G
E
I
R
D
P
Y
L
K
Q
H
L
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519046
1069
121143
Y431
D
G
D
I
R
D
P
Y
L
K
E
H
Y
V
K
Chicken
Gallus gallus
Q9DGG6
1334
149273
Q545
K
V
T
E
R
V
G
Q
S
A
V
A
D
Q
L
Frog
Xenopus laevis
P98999
1305
145393
Q550
M
V
V
E
R
L
G
Q
I
V
A
A
D
Q
L
Zebra Danio
Brachydanio rerio
NP_001093457
1139
128958
Y499
N
G
Q
S
R
D
S
Y
L
K
E
H
G
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW60
1307
142798
P493
E
S
Y
L
I
V
P
P
K
P
A
Y
T
Y
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780688
889
100312
P322
F
Q
Q
I
A
T
M
P
V
P
K
S
V
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.3
99.2
93.3
N.A.
94.4
94.5
N.A.
86.8
26.7
27.5
75.3
N.A.
34.6
N.A.
N.A.
39.4
Protein Similarity:
100
71
99.7
94.9
N.A.
96.4
96.6
N.A.
91.9
44
44.7
84.1
N.A.
51.1
N.A.
N.A.
53.3
P-Site Identity:
100
0
100
0
N.A.
93.3
93.3
N.A.
86.6
6.6
6.6
46.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
100
13.3
N.A.
100
100
N.A.
93.3
6.6
13.3
66.6
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
9
17
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
42
9
25
9
9
50
9
0
0
0
0
0
17
0
0
% D
% Glu:
9
9
17
17
0
0
0
0
0
9
17
0
9
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
50
9
0
0
0
17
0
0
0
0
9
9
9
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
50
9
0
0
% H
% Ile:
0
0
0
50
17
0
0
0
9
0
0
0
0
9
0
% I
% Lys:
9
0
0
0
0
0
0
0
9
50
17
0
0
0
42
% K
% Leu:
0
0
0
9
0
9
0
9
50
9
9
0
34
9
25
% L
% Met:
17
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
50
25
0
17
0
0
0
9
0
% P
% Gln:
0
9
17
0
0
0
0
17
0
0
34
9
0
17
0
% Q
% Arg:
0
0
0
9
67
9
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
9
0
9
0
0
9
0
9
0
0
9
0
0
9
% S
% Thr:
0
0
9
0
0
9
0
0
0
0
0
0
9
0
9
% T
% Val:
0
17
9
0
0
17
0
0
9
9
9
0
9
42
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
9
50
9
0
0
9
9
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _