KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY2
All Species:
25.15
Human Site:
Y788
Identified Species:
50.3
UniProt:
Q08462
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08462
NP_065433.2
1091
123603
Y788
H
A
H
V
L
G
D
Y
S
Q
V
L
F
E
R
Chimpanzee
Pan troglodytes
XP_509874
1077
119824
Y774
E
C
L
I
V
R
L
Y
L
G
P
L
D
S
R
Rhesus Macaque
Macaca mulatta
XP_001083524
1091
123478
Y788
H
A
H
V
L
G
D
Y
S
Q
V
L
F
E
R
Dog
Lupus familis
XP_535798
1051
118761
Y748
H
A
H
V
L
D
D
Y
S
Q
V
L
F
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80TL1
1090
123251
Y787
H
A
H
V
L
D
A
Y
S
Q
V
L
F
Q
R
Rat
Rattus norvegicus
P26769
1090
123297
Y787
H
A
H
V
L
D
A
Y
S
Q
V
L
F
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519046
1069
121143
Y766
H
A
S
I
L
D
E
Y
S
K
V
L
Y
E
R
Chicken
Gallus gallus
Q9DGG6
1334
149273
E928
L
C
P
D
S
S
V
E
T
L
H
L
D
L
A
Frog
Xenopus laevis
P98999
1305
145393
M888
Y
T
D
I
H
Y
T
M
F
L
C
S
A
L
L
Zebra Danio
Brachydanio rerio
NP_001093457
1139
128958
Y831
H
A
S
I
L
D
D
Y
S
M
A
L
Y
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW60
1307
142798
D1017
D
L
F
E
M
Y
N
D
A
N
I
T
H
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780688
889
100312
R628
R
R
I
E
Y
T
A
R
L
G
F
L
W
Q
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.3
99.2
93.3
N.A.
94.4
94.5
N.A.
86.8
26.7
27.5
75.3
N.A.
34.6
N.A.
N.A.
39.4
Protein Similarity:
100
71
99.7
94.9
N.A.
96.4
96.6
N.A.
91.9
44
44.7
84.1
N.A.
51.1
N.A.
N.A.
53.3
P-Site Identity:
100
20
100
93.3
N.A.
80
80
N.A.
60
6.6
0
46.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
100
93.3
N.A.
86.6
86.6
N.A.
86.6
13.3
13.3
66.6
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
0
0
0
0
25
0
9
0
9
0
9
0
9
% A
% Cys:
0
17
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
9
0
9
9
0
42
34
9
0
0
0
0
17
0
0
% D
% Glu:
9
0
0
17
0
0
9
9
0
0
0
0
0
34
0
% E
% Phe:
0
0
9
0
0
0
0
0
9
0
9
0
42
0
0
% F
% Gly:
0
0
0
0
0
17
0
0
0
17
0
0
0
9
0
% G
% His:
59
0
42
0
9
0
0
0
0
0
9
0
9
0
0
% H
% Ile:
0
0
9
34
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% K
% Leu:
9
9
9
0
59
0
9
0
17
17
0
84
0
17
17
% L
% Met:
0
0
0
0
9
0
0
9
0
9
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
42
0
0
0
25
0
% Q
% Arg:
9
9
0
0
0
9
0
9
0
0
0
0
0
0
59
% R
% Ser:
0
0
17
0
9
9
0
0
59
0
0
9
0
9
0
% S
% Thr:
0
9
0
0
0
9
9
0
9
0
0
9
0
0
9
% T
% Val:
0
0
0
42
9
0
9
0
0
0
50
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
9
0
0
0
9
17
0
67
0
0
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _