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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY2
All Species:
26.67
Human Site:
Y967
Identified Species:
53.33
UniProt:
Q08462
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08462
NP_065433.2
1091
123603
Y967
S
Q
E
P
E
R
Q
Y
M
H
I
G
T
M
V
Chimpanzee
Pan troglodytes
XP_509874
1077
119824
C953
Q
Q
D
A
E
R
S
C
S
H
L
G
T
M
V
Rhesus Macaque
Macaca mulatta
XP_001083524
1091
123478
Y967
A
Q
E
P
E
R
Q
Y
M
H
I
G
T
M
V
Dog
Lupus familis
XP_535798
1051
118761
Y927
A
Q
E
P
E
R
Q
Y
M
H
I
G
T
M
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80TL1
1090
123251
Y966
A
Q
E
P
E
R
Q
Y
M
H
I
G
T
M
V
Rat
Rattus norvegicus
P26769
1090
123297
Y966
A
Q
E
P
E
R
Q
Y
M
H
I
G
T
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519046
1069
121143
Y945
T
Q
E
P
D
R
Q
Y
M
H
I
G
T
M
V
Chicken
Gallus gallus
Q9DGG6
1334
149273
Q1118
N
H
P
H
G
H
L
Q
T
L
F
E
F
A
K
Frog
Xenopus laevis
P98999
1305
145393
Q1127
S
Q
P
H
R
H
L
Q
T
L
F
E
F
A
K
Zebra Danio
Brachydanio rerio
NP_001093457
1139
128958
Y1015
A
Q
Y
H
D
R
Q
Y
M
H
I
G
T
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW60
1307
142798
E1190
T
D
E
K
R
T
E
E
H
N
V
V
I
L
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780688
889
100312
L782
L
Q
D
K
L
E
Q
L
N
K
Q
A
F
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.3
99.2
93.3
N.A.
94.4
94.5
N.A.
86.8
26.7
27.5
75.3
N.A.
34.6
N.A.
N.A.
39.4
Protein Similarity:
100
71
99.7
94.9
N.A.
96.4
96.6
N.A.
91.9
44
44.7
84.1
N.A.
51.1
N.A.
N.A.
53.3
P-Site Identity:
100
53.3
93.3
93.3
N.A.
93.3
93.3
N.A.
86.6
0
13.3
73.3
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
66.6
100
100
N.A.
100
100
N.A.
100
6.6
13.3
86.6
N.A.
46.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
0
9
0
0
0
0
0
0
0
9
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
9
17
0
17
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
59
0
50
9
9
9
0
0
0
17
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
17
0
25
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
67
0
0
0
% G
% His:
0
9
0
25
0
17
0
0
9
67
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
59
0
9
0
0
% I
% Lys:
0
0
0
17
0
0
0
0
0
9
0
0
0
0
17
% K
% Leu:
9
0
0
0
9
0
17
9
0
17
9
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
59
0
0
0
0
67
0
% M
% Asn:
9
0
0
0
0
0
0
0
9
9
0
0
0
9
0
% N
% Pro:
0
0
17
50
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
84
0
0
0
0
67
17
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
17
67
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% S
% Thr:
17
0
0
0
0
9
0
0
17
0
0
0
67
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
75
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _