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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP4F3
All Species:
16.36
Human Site:
T277
Identified Species:
60
UniProt:
Q08477
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08477
NP_000887.2
520
59847
T277
V
I
Q
E
R
R
R
T
L
P
S
Q
G
V
D
Chimpanzee
Pan troglodytes
XP_001172535
520
59836
T277
V
I
Q
E
R
R
R
T
L
P
S
Q
G
V
D
Rhesus Macaque
Macaca mulatta
XP_001112226
520
59954
T277
V
I
Q
E
R
R
R
T
L
P
S
Q
G
V
E
Dog
Lupus familis
XP_541982
465
53642
R260
Q
R
F
R
R
A
C
R
L
V
H
N
F
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99N16
524
59823
T277
V
I
R
E
R
R
R
T
L
L
D
Q
G
G
D
Rat
Rattus norvegicus
Q3MID2
524
59887
T277
V
I
R
E
R
R
C
T
L
P
D
Q
G
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27589
501
57896
N260
E
R
R
E
T
L
V
N
N
S
K
E
T
T
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
95.3
76.7
N.A.
80.9
81.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
35.3
N.A.
N.A.
N.A.
Protein Similarity:
100
96.3
97.3
83.2
N.A.
88.1
88.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
55.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
20
N.A.
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
29
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
29
0
0
0
72
% D
% Glu:
15
0
0
86
0
0
0
0
0
0
0
15
0
0
15
% E
% Phe:
0
0
15
0
0
0
0
0
0
0
0
0
15
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
72
29
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% H
% Ile:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% K
% Leu:
0
0
0
0
0
15
0
0
86
15
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
15
0
0
15
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
58
0
0
0
0
15
% P
% Gln:
15
0
43
0
0
0
0
0
0
0
0
72
0
0
0
% Q
% Arg:
0
29
43
15
86
72
58
15
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
15
43
0
0
0
0
% S
% Thr:
0
0
0
0
15
0
0
72
0
0
0
0
15
29
0
% T
% Val:
72
0
0
0
0
0
15
0
0
15
0
0
0
43
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _