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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DSC1 All Species: 16.67
Human Site: S132 Identified Species: 40.74
UniProt: Q08554 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08554 NP_004939.1 894 99987 S132 K D T A L K R S K R R W A P I
Chimpanzee Pan troglodytes XP_512078 894 100054 S132 K D T A L K R S K R R W A P I
Rhesus Macaque Macaca mulatta XP_001098098 861 96213 S132 K D T A L K R S K R R W A P I
Dog Lupus familis XP_547623 893 100108 R132 V L K R S K R R W A P I P C S
Cat Felis silvestris
Mouse Mus musculus P55849 886 98935 S132 K E P V H N R S K R R W A P I
Rat Rattus norvegicus Q9Z1Y3 906 99668 Q157 H S G A L Q R Q K R D W V I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515354 1013 112098 T257 K N T V L K R T K R K W A P I
Chicken Gallus gallus P10288 912 100446 Q162 D S S H L K R Q K R D W V I P
Frog Xenopus laevis P33147 906 100375 Q158 K H N G L Q R Q K R D W V I P
Zebra Danio Brachydanio rerio Q90275 893 98972 V144 G D D S V N R V K R D W V I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 89.1 85 N.A. 81.6 34.2 N.A. 59.4 34.2 32.4 32 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 92.9 91 N.A. 89.8 51.2 N.A. 71.6 50.8 49.8 51.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 66.6 40 N.A. 73.3 40 40 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 73.3 46.6 N.A. 93.3 46.6 46.6 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 40 0 0 0 0 0 10 0 0 50 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 10 40 10 0 0 0 0 0 0 0 40 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 10 10 0 10 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 40 50 % I
% Lys: 60 0 10 0 0 60 0 0 90 0 10 0 0 0 0 % K
% Leu: 0 10 0 0 70 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 10 0 0 20 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 10 0 10 50 40 % P
% Gln: 0 0 0 0 0 20 0 30 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 0 0 100 10 0 90 40 0 0 0 0 % R
% Ser: 0 20 10 10 10 0 0 40 0 0 0 0 0 0 10 % S
% Thr: 0 0 40 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 10 0 0 20 10 0 0 10 0 0 0 0 40 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 90 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _