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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DSC1
All Species:
8.79
Human Site:
S91
Identified Species:
21.48
UniProt:
Q08554
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08554
NP_004939.1
894
99987
S91
I
L
S
S
E
R
K
S
F
S
I
F
L
S
D
Chimpanzee
Pan troglodytes
XP_512078
894
100054
S91
I
L
S
S
E
R
K
S
F
S
I
F
L
S
D
Rhesus Macaque
Macaca mulatta
XP_001098098
861
96213
S91
I
L
S
S
E
R
K
S
F
S
I
F
L
S
G
Dog
Lupus familis
XP_547623
893
100108
I91
S
E
R
K
S
F
S
I
F
P
S
D
S
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
P55849
886
98935
G91
L
L
S
S
E
K
R
G
F
S
I
L
L
S
D
Rat
Rattus norvegicus
Q9Z1Y3
906
99668
Q116
K
E
T
Q
E
K
W
Q
V
A
V
N
L
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515354
1013
112098
A216
R
L
S
S
E
Q
K
A
F
T
I
L
L
S
D
Chicken
Gallus gallus
P10288
912
100446
Q121
K
E
T
Q
E
E
W
Q
M
K
V
K
L
T
P
Frog
Xenopus laevis
P33147
906
100375
L117
Q
D
E
D
T
R
E
L
W
H
V
T
V
K
I
Zebra Danio
Brachydanio rerio
Q90275
893
98972
K103
Q
S
L
E
I
K
A
K
D
E
N
S
Q
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
89.1
85
N.A.
81.6
34.2
N.A.
59.4
34.2
32.4
32
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
92.9
91
N.A.
89.8
51.2
N.A.
71.6
50.8
49.8
51.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
66.6
20
N.A.
66.6
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
6.6
N.A.
86.6
46.6
N.A.
86.6
33.3
33.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
0
0
10
0
0
10
0
0
40
% D
% Glu:
0
30
10
10
70
10
10
0
0
10
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
60
0
0
30
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
30
0
0
0
10
0
0
10
0
0
50
0
0
0
10
% I
% Lys:
20
0
0
10
0
30
40
10
0
10
0
10
0
10
0
% K
% Leu:
10
50
10
0
0
0
0
10
0
0
0
20
70
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% P
% Gln:
20
0
0
20
0
10
0
20
0
0
0
0
10
10
10
% Q
% Arg:
10
0
10
0
0
40
10
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
50
50
10
0
10
30
0
40
10
10
10
60
10
% S
% Thr:
0
0
20
0
10
0
0
0
0
10
0
10
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
30
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
20
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _