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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPID
All Species:
24.55
Human Site:
T223
Identified Species:
33.75
UniProt:
Q08752
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08752
NP_005029.1
370
40764
T223
V
D
K
I
L
L
I
T
E
D
L
K
N
I
G
Chimpanzee
Pan troglodytes
XP_001145793
370
40802
T223
V
D
K
I
L
L
I
T
E
D
L
K
N
I
G
Rhesus Macaque
Macaca mulatta
XP_001097233
370
40963
T223
V
D
K
I
L
L
I
T
E
D
L
K
N
I
G
Dog
Lupus familis
XP_532704
370
40997
T223
V
N
K
I
L
L
I
T
E
D
L
K
N
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR16
370
40724
S223
V
D
K
I
L
L
I
S
E
D
L
K
N
I
G
Rat
Rattus norvegicus
Q6DGG0
370
40747
S223
V
D
K
I
L
L
I
S
E
D
L
K
N
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510363
402
44737
T255
K
E
V
D
K
I
L
T
V
A
E
D
I
K
N
Chicken
Gallus gallus
XP_426283
360
39409
L213
P
E
D
S
D
I
D
L
K
D
V
L
K
G
V
Frog
Xenopus laevis
NP_001087854
370
41012
A223
V
E
R
I
T
S
I
A
E
N
V
K
N
I
G
Zebra Danio
Brachydanio rerio
NP_001002065
371
41263
E224
D
K
V
L
S
V
A
E
D
L
K
N
I
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52011
173
18532
H54
G
K
S
G
K
P
L
H
F
K
G
S
K
F
H
Sea Urchin
Strong. purpuratus
XP_001201326
373
41658
K225
L
E
V
A
M
K
L
K
D
I
G
N
G
K
Y
Poplar Tree
Populus trichocarpa
XP_002306460
361
40200
S214
W
W
M
K
A
V
D
S
I
K
A
F
G
N
E
Maize
Zea mays
P21569
172
18330
L53
V
G
K
S
G
K
P
L
H
Y
K
G
S
T
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C566
361
40588
F214
W
W
M
E
T
V
D
F
V
K
A
H
G
N
E
Baker's Yeast
Sacchar. cerevisiae
P53691
371
42053
I219
F
D
T
V
L
K
A
I
E
T
V
K
N
I
G
Red Bread Mold
Neurospora crassa
Q9P3X9
375
40552
A222
A
S
K
I
L
K
I
A
T
D
C
K
D
F
G
Conservation
Percent
Protein Identity:
100
99.1
97.5
93.2
N.A.
94.3
93.5
N.A.
74.8
78.3
76.4
71.9
N.A.
N.A.
N.A.
34.8
48.5
Protein Similarity:
100
99.7
98.6
96.2
N.A.
96.2
96.2
N.A.
83.5
86.7
88.6
85.4
N.A.
N.A.
N.A.
38.9
67.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
6.6
6.6
53.3
0
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
33.3
80
20
N.A.
N.A.
N.A.
6.6
33.3
Percent
Protein Identity:
48.6
34.5
N.A.
47.5
46
52
Protein Similarity:
65.4
39.7
N.A.
62.7
61.1
64.5
P-Site Identity:
0
13.3
N.A.
0
46.6
46.6
P-Site Similarity:
13.3
20
N.A.
6.6
60
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
6
6
0
12
12
0
6
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% C
% Asp:
6
36
6
6
6
0
18
0
12
48
0
6
6
0
0
% D
% Glu:
0
24
0
6
0
0
0
6
48
0
6
0
0
0
12
% E
% Phe:
6
0
0
0
0
0
0
6
6
0
0
6
0
12
6
% F
% Gly:
6
6
0
6
6
0
0
0
0
0
12
6
18
12
53
% G
% His:
0
0
0
0
0
0
0
6
6
0
0
6
0
0
6
% H
% Ile:
0
0
0
48
0
12
48
6
6
6
0
0
12
48
0
% I
% Lys:
6
12
48
6
12
24
0
6
6
18
12
53
12
12
0
% K
% Leu:
6
0
0
6
48
36
18
12
0
6
36
6
0
0
0
% L
% Met:
0
0
12
0
6
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
0
0
0
0
0
0
6
0
12
48
12
12
% N
% Pro:
6
0
0
0
0
6
6
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
6
6
12
6
6
0
18
0
0
0
6
6
0
0
% S
% Thr:
0
0
6
0
12
0
0
30
6
6
0
0
0
6
0
% T
% Val:
48
0
18
6
0
18
0
0
12
0
18
0
0
0
6
% V
% Trp:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _