KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RBL2
All Species:
18.79
Human Site:
S270
Identified Species:
34.44
UniProt:
Q08999
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08999
NP_005602.3
1139
128367
S270
A
K
D
S
K
P
S
S
D
P
P
C
I
I
E
Chimpanzee
Pan troglodytes
XP_523371
1139
128318
S270
A
K
D
S
K
P
S
S
D
P
P
C
I
I
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535303
1139
128252
S270
A
K
D
S
K
P
S
S
D
P
P
C
V
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q64700
1135
127455
S267
P
K
D
S
K
A
S
S
D
P
P
C
V
I
E
Rat
Rattus norvegicus
O55081
1135
127799
S267
P
R
D
S
H
P
S
S
D
P
P
C
V
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520195
1071
120785
G253
F
D
K
K
L
L
K
G
K
E
E
S
L
T
G
Chicken
Gallus gallus
Q90600
921
104417
S108
T
E
L
L
K
S
L
S
I
S
V
C
T
F
F
Frog
Xenopus laevis
NP_001084880
998
113114
P185
N
K
E
D
L
L
N
P
S
F
T
A
K
L
A
Zebra Danio
Brachydanio rerio
XP_002667000
970
107485
R157
F
I
K
K
L
F
E
R
K
I
L
K
G
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24472
845
96808
Y32
L
E
M
I
N
A
E
Y
T
N
L
C
R
D
L
Honey Bee
Apis mellifera
XP_395096
1006
113492
N193
D
I
S
D
D
L
V
N
S
Y
H
L
L
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
R222
W
L
L
F
L
A
L
R
V
H
A
F
S
R
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKZ3
1013
112157
A200
F
G
W
L
L
F
L
A
L
R
N
H
A
F
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
97.1
N.A.
90.9
90
N.A.
79.8
21.8
43.2
53
N.A.
23.5
40.2
N.A.
N.A.
Protein Similarity:
100
99.9
N.A.
98.7
N.A.
94.9
94.8
N.A.
87.1
38.3
61.2
65.5
N.A.
40.6
57.5
N.A.
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
80
73.3
N.A.
0
20
6.6
6.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
6.6
26.6
26.6
6.6
N.A.
13.3
20
N.A.
N.A.
Percent
Protein Identity:
20.3
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
39.6
N.A.
N.A.
39.3
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
0
0
24
0
8
0
0
8
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
54
0
0
0
% C
% Asp:
8
8
39
16
8
0
0
0
39
0
0
0
0
8
0
% D
% Glu:
0
16
8
0
0
0
16
0
0
8
8
0
0
0
47
% E
% Phe:
24
0
0
8
0
16
0
0
0
8
0
8
0
16
16
% F
% Gly:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
8
8
8
0
0
0
% H
% Ile:
0
16
0
8
0
0
0
0
8
8
0
0
16
39
0
% I
% Lys:
0
39
16
16
39
0
8
0
16
0
0
8
8
8
0
% K
% Leu:
8
8
16
16
39
24
24
0
8
0
16
8
16
16
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
8
8
0
8
8
0
0
0
0
% N
% Pro:
16
0
0
0
0
31
0
8
0
39
39
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
16
0
8
0
0
8
8
0
% R
% Ser:
0
0
8
39
0
8
39
47
16
8
0
8
8
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
8
0
8
0
8
8
0
% T
% Val:
0
0
0
0
0
0
8
0
8
0
8
0
24
0
8
% V
% Trp:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _