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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBL2 All Species: 19.09
Human Site: T618 Identified Species: 35
UniProt: Q08999 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08999 NP_005602.3 1139 128367 T618 D N E N R V P T C E E V M P P
Chimpanzee Pan troglodytes XP_523371 1139 128318 T618 D N E N R V P T C E E V M P P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535303 1139 128252 T617 D N E N R V P T C E E V M P P
Cat Felis silvestris
Mouse Mus musculus Q64700 1135 127455 T615 D N E N R V P T C E E V M P P
Rat Rattus norvegicus O55081 1135 127799 T615 D N E N R V P T C E E V T P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520195 1071 120785 L568 E V M P P Q N L E R G D G G V
Chicken Gallus gallus Q90600 921 104417 A421 H I F K K K F A E A V G Q G C
Frog Xenopus laevis NP_001084880 998 113114 E498 I E V F I R S E D G L S R D M
Zebra Danio Brachydanio rerio XP_002667000 970 107485 Q470 K N C V P T C Q E V M P P Q H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24472 845 96808 A345 Y D A G E H T A L N D Q S L R
Honey Bee Apis mellifera XP_395096 1006 113492 S506 C L E I V I Y S Y K S N D K I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa B9GLX8 1035 114624 I535 M C T A E A Q I L H A T N L T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LKZ3 1013 112157 A513 A E A Q I L H A N N L N S L L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 97.1 N.A. 90.9 90 N.A. 79.8 21.8 43.2 53 N.A. 23.5 40.2 N.A. N.A.
Protein Similarity: 100 99.9 N.A. 98.7 N.A. 94.9 94.8 N.A. 87.1 38.3 61.2 65.5 N.A. 40.6 57.5 N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 0 0 0 6.6 N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 6.6 6.6 0 6.6 N.A. 13.3 26.6 N.A. N.A.
Percent
Protein Identity: 20.3 N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: 39.6 N.A. N.A. 39.3 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 8 0 8 0 24 0 8 8 0 0 0 0 % A
% Cys: 8 8 8 0 0 0 8 0 39 0 0 0 0 0 8 % C
% Asp: 39 8 0 0 0 0 0 0 8 0 8 8 8 8 0 % D
% Glu: 8 16 47 0 16 0 0 8 24 39 39 0 0 0 0 % E
% Phe: 0 0 8 8 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 0 8 8 8 8 16 0 % G
% His: 8 0 0 0 0 8 8 0 0 8 0 0 0 0 8 % H
% Ile: 8 8 0 8 16 8 0 8 0 0 0 0 0 0 8 % I
% Lys: 8 0 0 8 8 8 0 0 0 8 0 0 0 8 0 % K
% Leu: 0 8 0 0 0 8 0 8 16 0 16 0 0 24 8 % L
% Met: 8 0 8 0 0 0 0 0 0 0 8 0 31 0 8 % M
% Asn: 0 47 0 39 0 0 8 0 8 16 0 16 8 0 0 % N
% Pro: 0 0 0 8 16 0 39 0 0 0 0 8 8 39 39 % P
% Gln: 0 0 0 8 0 8 8 8 0 0 0 8 8 8 0 % Q
% Arg: 0 0 0 0 39 8 0 0 0 8 0 0 8 0 8 % R
% Ser: 0 0 0 0 0 0 8 8 0 0 8 8 16 0 0 % S
% Thr: 0 0 8 0 0 8 8 39 0 0 0 8 8 0 8 % T
% Val: 0 8 8 8 8 39 0 0 0 8 8 39 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _