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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBL2 All Species: 19.7
Human Site: T642 Identified Species: 36.11
UniProt: Q08999 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08999 NP_005602.3 1139 128367 T642 C I A G S P L T P R R V T E V
Chimpanzee Pan troglodytes XP_523371 1139 128318 T642 C I A G S P L T P R R V T E V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535303 1139 128252 T641 C I A G S P L T P R R V S E V
Cat Felis silvestris
Mouse Mus musculus Q64700 1135 127455 T639 Y I A G S P L T P R R V G E V
Rat Rattus norvegicus O55081 1135 127799 T639 Y I A G S P L T P R R V G E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520195 1071 120785 T586 P M T P R R V T E V R A E T G
Chicken Gallus gallus Q90600 921 104417 G439 G S Q R Y Q L G V R L Y Y R V
Frog Xenopus laevis NP_001084880 998 113114 I516 L N T I E E Q I L E S R A W T
Zebra Danio Brachydanio rerio XP_002667000 970 107485 T488 G S G S N A N T P S S K T E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24472 845 96808 D363 T P L T R K Q D L P A Q P A M
Honey Bee Apis mellifera XP_395096 1006 113492 D524 I L N A L N L D A Y Y F Y K V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa B9GLX8 1035 114624 C553 T N E R F H R C M L A C S A E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LKZ3 1013 112157 A531 R F H R C M L A C S A E L V L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 97.1 N.A. 90.9 90 N.A. 79.8 21.8 43.2 53 N.A. 23.5 40.2 N.A. N.A.
Protein Similarity: 100 99.9 N.A. 98.7 N.A. 94.9 94.8 N.A. 87.1 38.3 61.2 65.5 N.A. 40.6 57.5 N.A. N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 86.6 86.6 N.A. 13.3 20 0 26.6 N.A. 0 13.3 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 86.6 N.A. 26.6 20 0 33.3 N.A. 6.6 26.6 N.A. N.A.
Percent
Protein Identity: 20.3 N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: 39.6 N.A. N.A. 39.3 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 39 8 0 8 0 8 8 0 24 8 8 16 0 % A
% Cys: 24 0 0 0 8 0 0 8 8 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 8 8 0 0 8 8 0 8 8 47 8 % E
% Phe: 0 8 0 0 8 0 0 0 0 0 0 8 0 0 8 % F
% Gly: 16 0 8 39 0 0 0 8 0 0 0 0 16 0 8 % G
% His: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 39 0 8 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 0 8 0 8 0 % K
% Leu: 8 8 8 0 8 0 62 0 16 8 8 0 8 0 8 % L
% Met: 0 8 0 0 0 8 0 0 8 0 0 0 0 0 8 % M
% Asn: 0 16 8 0 8 8 8 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 0 8 0 39 0 0 47 8 0 0 8 0 0 % P
% Gln: 0 0 8 0 0 8 16 0 0 0 0 8 0 0 0 % Q
% Arg: 8 0 0 24 16 8 8 0 0 47 47 8 0 8 0 % R
% Ser: 0 16 0 8 39 0 0 0 0 16 16 0 16 0 0 % S
% Thr: 16 0 16 8 0 0 0 54 0 0 0 0 24 8 8 % T
% Val: 0 0 0 0 0 0 8 0 8 8 0 39 0 8 54 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 16 0 0 0 8 0 0 0 0 8 8 8 16 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _