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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBL2 All Species: 14.24
Human Site: T974 Identified Species: 26.11
UniProt: Q08999 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08999 NP_005602.3 1139 128367 T974 P V M R S S S T L P V P Q P S
Chimpanzee Pan troglodytes XP_523371 1139 128318 T974 P V M R S S S T L P V P Q P S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535303 1139 128252 T973 P V M R S S S T L P V P Q P S
Cat Felis silvestris
Mouse Mus musculus Q64700 1135 127455 P970 M R S N S T L P V P Q P S S A
Rat Rattus norvegicus O55081 1135 127799 P970 M R S N S T L P V P Q P S S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520195 1071 120785 T905 P V M R S S S T L P V P Q P N
Chicken Gallus gallus Q90600 921 104417 K757 L V F M Q K L K T N I L Q Y A
Frog Xenopus laevis NP_001084880 998 113114 T834 T S Q D V E M T A S N S N D S
Zebra Danio Brachydanio rerio XP_002667000 970 107485 P806 S T L P I P Q P S S A P S T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24472 845 96808 I681 Y R E V F I D I N E D G E P K
Honey Bee Apis mellifera XP_395096 1006 113492 V842 V S D K E T N V A P P T P T N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa B9GLX8 1035 114624 I871 T G Q D H V D I I T F Y N E I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LKZ3 1013 112157 N849 V D I I T F Y N E I F I P A V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 97.1 N.A. 90.9 90 N.A. 79.8 21.8 43.2 53 N.A. 23.5 40.2 N.A. N.A.
Protein Similarity: 100 99.9 N.A. 98.7 N.A. 94.9 94.8 N.A. 87.1 38.3 61.2 65.5 N.A. 40.6 57.5 N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 20 20 N.A. 93.3 13.3 13.3 6.6 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 40 40 N.A. 100 26.6 13.3 13.3 N.A. 13.3 33.3 N.A. N.A.
Percent
Protein Identity: 20.3 N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: 39.6 N.A. N.A. 39.3 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 16 0 8 0 0 8 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 16 0 0 16 0 0 0 8 0 0 8 0 % D
% Glu: 0 0 8 0 8 8 0 0 8 8 0 0 8 8 0 % E
% Phe: 0 0 8 0 8 8 0 0 0 0 16 0 0 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 8 8 0 16 8 8 8 8 0 0 8 % I
% Lys: 0 0 0 8 0 8 0 8 0 0 0 0 0 0 8 % K
% Leu: 8 0 8 0 0 0 24 0 31 0 0 8 0 0 0 % L
% Met: 16 0 31 8 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 16 0 0 8 8 8 8 8 0 16 0 16 % N
% Pro: 31 0 0 8 0 8 0 24 0 54 8 54 16 39 8 % P
% Gln: 0 0 16 0 8 0 8 0 0 0 16 0 39 0 0 % Q
% Arg: 0 24 0 31 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 16 16 0 47 31 31 0 8 16 0 8 24 16 31 % S
% Thr: 16 8 0 0 8 24 0 39 8 8 0 8 0 16 0 % T
% Val: 16 39 0 8 8 8 0 8 16 0 31 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 8 0 0 0 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _