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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLFN5 All Species: 13.33
Human Site: T571 Identified Species: 73.33
UniProt: Q08AF3 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08AF3 NP_659412.3 891 101055 T571 L S K N L R K T R E L F V H G
Chimpanzee Pan troglodytes XP_523607 891 100906 T571 L S K N L R K T R E L F V H G
Rhesus Macaque Macaca mulatta XP_001113957 889 100896 T571 L S K N L R K T K E L F V H G
Dog Lupus familis XP_548260 934 105691 T608 L S E S L Q E T R E L F I H C
Cat Felis silvestris
Mouse Mus musculus Q8CBA2 884 100801 H567 L S T N L S K H R E M F V H G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 92.4 41.1 N.A. 58.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 95.2 60.5 N.A. 75 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 60 N.A. 73.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 80 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 20 0 0 0 20 0 0 100 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 % G
% His: 0 0 0 0 0 0 0 20 0 0 0 0 0 100 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % I
% Lys: 0 0 60 0 0 0 80 0 20 0 0 0 0 0 0 % K
% Leu: 100 0 0 0 100 0 0 0 0 0 80 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % M
% Asn: 0 0 0 80 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 60 0 0 80 0 0 0 0 0 0 % R
% Ser: 0 100 0 20 0 20 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 20 0 0 0 0 80 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 80 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _