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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAC14 All Species: 21.82
Human Site: S491 Identified Species: 32
UniProt: Q08AM6 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08AM6 NP_060522.3 782 87973 S491 D G P D L Q A S H S E L Q V P
Chimpanzee Pan troglodytes XP_001170940 782 87966 S491 D G P D L Q A S H S E L Q V P
Rhesus Macaque Macaca mulatta XP_001106962 782 87966 S491 D G P D L R A S H S E L Q V P
Dog Lupus familis XP_546837 783 88300 S492 D G P D F R V S H S E L Q V P
Cat Felis silvestris
Mouse Mus musculus Q80WQ2 782 88029 N491 D G P D L R V N H S E L Q V P
Rat Rattus norvegicus Q80W92 783 88049 N492 D G P D L Q V N H S E L Q V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506866 755 85069 S464 D S P D L R V S Q S E L Q V P
Chicken Gallus gallus Q5ZIW5 780 87805 G491 E A A E P R P G Q V E L H V P
Frog Xenopus laevis Q68F38 782 88899 S493 N D L P T G M S E L H V P V P
Zebra Danio Brachydanio rerio Q66L58 771 87538 T494 C D I S D S K T E L H I P G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650208 687 78014 L426 N S Q E S R E L N D F N K S H
Honey Bee Apis mellifera XP_396938 661 75158 A400 A A I T D S N A E M Q N K Y F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784614 749 84020 P458 Q E T N Q I A P S A A S N A S
Poplar Tree Populus trichocarpa XP_002314784 724 81260 S454 E R V Y R E L S T I L E G E A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_565275 743 83893 T470 D N L D F A S T M V Q A L N L
Baker's Yeast Sacchar. cerevisiae Q06708 880 99754 S521 Q I L K H N D S M F L T L L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 96.4 N.A. 94.1 94.5 N.A. 80 85.1 81 80.9 N.A. 44.3 47.7 N.A. 55.7
Protein Similarity: 100 99.8 99.6 97.3 N.A. 96.4 96.1 N.A. 84.6 90.6 88.2 88.6 N.A. 61.8 64.9 N.A. 69.4
P-Site Identity: 100 100 93.3 80 N.A. 80 86.6 N.A. 73.3 26.6 20 0 N.A. 0 0 N.A. 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 80 46.6 33.3 13.3 N.A. 33.3 20 N.A. 20
Percent
Protein Identity: 30 N.A. N.A. 29.8 27.9 N.A.
Protein Similarity: 48.7 N.A. N.A. 47.3 48 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 20 N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 13 7 0 0 7 25 7 0 7 7 7 0 7 7 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 50 13 0 50 13 0 7 0 0 7 0 0 0 0 0 % D
% Glu: 13 7 0 13 0 7 7 0 19 0 50 7 0 7 0 % E
% Phe: 0 0 0 0 13 0 0 0 0 7 7 0 0 0 7 % F
% Gly: 0 38 0 0 0 7 0 7 0 0 0 0 7 7 0 % G
% His: 0 0 0 0 7 0 0 0 38 0 13 0 7 0 7 % H
% Ile: 0 7 13 0 0 7 0 0 0 7 0 7 0 0 0 % I
% Lys: 0 0 0 7 0 0 7 0 0 0 0 0 13 0 7 % K
% Leu: 0 0 19 0 38 0 7 7 0 13 13 50 13 7 7 % L
% Met: 0 0 0 0 0 0 7 0 13 7 0 0 0 0 0 % M
% Asn: 13 7 0 7 0 7 7 13 7 0 0 13 7 7 0 % N
% Pro: 0 0 44 7 7 0 7 7 0 0 0 0 13 0 57 % P
% Gln: 13 0 7 0 7 19 0 0 13 0 13 0 44 0 0 % Q
% Arg: 0 7 0 0 7 38 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 13 0 7 7 13 7 50 7 44 0 7 0 7 13 % S
% Thr: 0 0 7 7 7 0 0 13 7 0 0 7 0 0 0 % T
% Val: 0 0 7 0 0 0 25 0 0 13 0 7 0 57 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _