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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAC14 All Species: 29.09
Human Site: S517 Identified Species: 42.67
UniProt: Q08AM6 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08AM6 NP_060522.3 782 87973 S517 G T K G L E C S P S T P T M N
Chimpanzee Pan troglodytes XP_001170940 782 87966 S517 G T K G L E C S P S T P T M N
Rhesus Macaque Macaca mulatta XP_001106962 782 87966 S517 G T K G L E C S P S T P T M N
Dog Lupus familis XP_546837 783 88300 S518 G T K G L E C S P S T P T M N
Cat Felis silvestris
Mouse Mus musculus Q80WQ2 782 88029 S517 S T K G L E G S P S T P T M N
Rat Rattus norvegicus Q80W92 783 88049 S518 N T K G L E C S P S T P T M N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506866 755 85069 S490 G P K A L E C S P Y T P T M N
Chicken Gallus gallus Q5ZIW5 780 87805 S517 K G L E C S P S T P T M N S Y
Frog Xenopus laevis Q68F38 782 88899 S519 R G L E C S P S T P T M N S Y
Zebra Danio Brachydanio rerio Q66L58 771 87538 F520 M N S Y F Y K F M I N L L K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650208 687 78014 L452 F S E E K L I L E N R A S L I
Honey Bee Apis mellifera XP_396938 661 75158 E426 S A D R H L L E E R G A F I I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784614 749 84020 L484 T D F M V K L L S L F S T D P
Poplar Tree Populus trichocarpa XP_002314784 724 81260 S480 L N L I L L T S S E L A E L R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_565275 743 83893 L496 R E L L K G S L V N R E G K E
Baker's Yeast Sacchar. cerevisiae Q06708 880 99754 S547 K A L S L L Q S L C S D S N D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 96.4 N.A. 94.1 94.5 N.A. 80 85.1 81 80.9 N.A. 44.3 47.7 N.A. 55.7
Protein Similarity: 100 99.8 99.6 97.3 N.A. 96.4 96.1 N.A. 84.6 90.6 88.2 88.6 N.A. 61.8 64.9 N.A. 69.4
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. 80 13.3 13.3 0 N.A. 0 0 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 86.6 93.3 N.A. 80 13.3 13.3 0 N.A. 33.3 6.6 N.A. 20
Percent
Protein Identity: 30 N.A. N.A. 29.8 27.9 N.A.
Protein Similarity: 48.7 N.A. N.A. 47.3 48 N.A.
P-Site Identity: 13.3 N.A. N.A. 0 13.3 N.A.
P-Site Similarity: 20 N.A. N.A. 6.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 7 0 0 0 0 0 0 0 19 0 0 0 % A
% Cys: 0 0 0 0 13 0 38 0 0 7 0 0 0 0 0 % C
% Asp: 0 7 7 0 0 0 0 0 0 0 0 7 0 7 7 % D
% Glu: 0 7 7 19 0 44 0 7 13 7 0 7 7 0 7 % E
% Phe: 7 0 7 0 7 0 0 7 0 0 7 0 7 0 0 % F
% Gly: 32 13 0 38 0 7 7 0 0 0 7 0 7 0 0 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 7 0 0 7 0 0 0 7 13 % I
% Lys: 13 0 44 0 13 7 7 0 0 0 0 0 0 13 0 % K
% Leu: 7 0 32 7 57 25 13 19 7 7 7 7 7 13 0 % L
% Met: 7 0 0 7 0 0 0 0 7 0 0 13 0 44 0 % M
% Asn: 7 13 0 0 0 0 0 0 0 13 7 0 13 7 44 % N
% Pro: 0 7 0 0 0 0 13 0 44 13 0 44 0 0 7 % P
% Gln: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Q
% Arg: 13 0 0 7 0 0 0 0 0 7 13 0 0 0 13 % R
% Ser: 13 7 7 7 0 13 7 69 13 38 7 7 13 13 0 % S
% Thr: 7 38 0 0 0 0 7 0 13 0 57 0 50 0 0 % T
% Val: 0 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 7 0 0 0 7 0 0 0 0 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _