Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAC14 All Species: 24.24
Human Site: S743 Identified Species: 35.56
UniProt: Q08AM6 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08AM6 NP_060522.3 782 87973 S743 P K S Q K A D S P S I D Y A E
Chimpanzee Pan troglodytes XP_001170940 782 87966 S743 P K S Q R A D S P S I D Y A E
Rhesus Macaque Macaca mulatta XP_001106962 782 87966 S743 P K S Q K A D S P S I D Y A E
Dog Lupus familis XP_546837 783 88300 S744 P K S Q K A D S P S I D Y A E
Cat Felis silvestris
Mouse Mus musculus Q80WQ2 782 88029 S743 P K S Q K G D S P S I D Y T E
Rat Rattus norvegicus Q80W92 783 88049 S744 P K S Q K G D S P S I D Y T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506866 755 85069 P716 P A S R Q A D P P S I D Y V E
Chicken Gallus gallus Q5ZIW5 780 87805 S741 A S S R R P A S S T I D Y T E
Frog Xenopus laevis Q68F38 782 88899 P743 S R A P K E D P A R I D Y V E
Zebra Danio Brachydanio rerio Q66L58 771 87538 Q733 V K D K H L A Q P H I D Y S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650208 687 78014 Q660 I D F D A L E Q H F I K L Q K
Honey Bee Apis mellifera XP_396938 661 75158 I634 E L L K H F H I I Q E Q H Q E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784614 749 84020 A692 L F L P G H K A A V G P R L A
Poplar Tree Populus trichocarpa XP_002314784 724 81260 V693 S S G T C K D V Q R L E E S Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_565275 743 83893 P715 Q Q Q Q Q R P P P S S T S S S
Baker's Yeast Sacchar. cerevisiae Q06708 880 99754 C770 Q R E N S N F C D S N S D I S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 96.4 N.A. 94.1 94.5 N.A. 80 85.1 81 80.9 N.A. 44.3 47.7 N.A. 55.7
Protein Similarity: 100 99.8 99.6 97.3 N.A. 96.4 96.1 N.A. 84.6 90.6 88.2 88.6 N.A. 61.8 64.9 N.A. 69.4
P-Site Identity: 100 93.3 100 100 N.A. 86.6 86.6 N.A. 66.6 40 40 40 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 80 60 53.3 53.3 N.A. 20 20 N.A. 6.6
Percent
Protein Identity: 30 N.A. N.A. 29.8 27.9 N.A.
Protein Similarity: 48.7 N.A. N.A. 47.3 48 N.A.
P-Site Identity: 6.6 N.A. N.A. 20 6.6 N.A.
P-Site Similarity: 33.3 N.A. N.A. 40 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 0 7 32 13 7 13 0 0 0 0 25 7 % A
% Cys: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 7 0 0 57 0 7 0 0 63 7 0 0 % D
% Glu: 7 0 7 0 0 7 7 0 0 0 7 7 7 0 69 % E
% Phe: 0 7 7 0 0 7 7 0 0 7 0 0 0 0 0 % F
% Gly: 0 0 7 0 7 13 0 0 0 0 7 0 0 0 0 % G
% His: 0 0 0 0 13 7 7 0 7 7 0 0 7 0 0 % H
% Ile: 7 0 0 0 0 0 0 7 7 0 69 0 0 7 0 % I
% Lys: 0 44 0 13 38 7 7 0 0 0 0 7 0 0 7 % K
% Leu: 7 7 13 0 0 13 0 0 0 0 7 0 7 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 7 0 0 0 0 7 0 0 0 0 % N
% Pro: 44 0 0 13 0 7 7 19 57 0 0 7 0 0 0 % P
% Gln: 13 7 7 44 13 0 0 13 7 7 0 7 0 13 7 % Q
% Arg: 0 13 0 13 13 7 0 0 0 13 0 0 7 0 0 % R
% Ser: 13 13 50 0 7 0 0 44 7 57 7 7 7 19 13 % S
% Thr: 0 0 0 7 0 0 0 0 0 7 0 7 0 19 0 % T
% Val: 7 0 0 0 0 0 0 7 0 7 0 0 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 63 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _