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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAC14 All Species: 4.55
Human Site: T352 Identified Species: 6.67
UniProt: Q08AM6 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08AM6 NP_060522.3 782 87973 T352 G Q R Q A E P T P D D A L P K
Chimpanzee Pan troglodytes XP_001170940 782 87966 T352 G Q R Q A E P T P D D A L P K
Rhesus Macaque Macaca mulatta XP_001106962 782 87966 A352 G Q R Q A E P A P D D A L P K
Dog Lupus familis XP_546837 783 88300 N353 V Q R Q A E P N P D D S V A K
Cat Felis silvestris
Mouse Mus musculus Q80WQ2 782 88029 P352 V A Q K Q T E P N P E D S L P
Rat Rattus norvegicus Q80W92 783 88049 N353 A Q K Q T E P N P E D S L P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506866 755 85069 D325 A P G R V G S D V D D S P V K
Chicken Gallus gallus Q5ZIW5 780 87805 P352 S I T L S A E P N P E E P V S
Frog Xenopus laevis Q68F38 782 88899 F354 A T Q P D E D F S S N H E N S
Zebra Danio Brachydanio rerio Q66L58 771 87538 P356 S Q T K S S P P S D E A P S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650208 687 78014 F288 I R E F V Q I F G P N V L P Y
Honey Bee Apis mellifera XP_396938 661 75158 M262 G P L M L P Y M S G I L V A V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784614 749 84020 K320 D Q K R K S I K E V A T S V N
Poplar Tree Populus trichocarpa XP_002314784 724 81260 E316 K I R V V A R E T N E E L R A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_565275 743 83893 D332 S I H V E P S D G F D V G A I
Baker's Yeast Sacchar. cerevisiae Q06708 880 99754 A368 E Q L L D S E A T S Q E P L R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 96.4 N.A. 94.1 94.5 N.A. 80 85.1 81 80.9 N.A. 44.3 47.7 N.A. 55.7
Protein Similarity: 100 99.8 99.6 97.3 N.A. 96.4 96.1 N.A. 84.6 90.6 88.2 88.6 N.A. 61.8 64.9 N.A. 69.4
P-Site Identity: 100 100 93.3 66.6 N.A. 0 60 N.A. 20 0 6.6 33.3 N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 100 93.3 80 N.A. 20 80 N.A. 33.3 13.3 20 53.3 N.A. 33.3 13.3 N.A. 20
Percent
Protein Identity: 30 N.A. N.A. 29.8 27.9 N.A.
Protein Similarity: 48.7 N.A. N.A. 47.3 48 N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 26.6 N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 7 0 0 25 13 0 13 0 0 7 25 0 19 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 13 0 7 13 0 38 44 7 0 0 0 % D
% Glu: 7 0 7 0 7 38 19 7 7 7 25 19 7 0 0 % E
% Phe: 0 0 0 7 0 0 0 13 0 7 0 0 0 0 0 % F
% Gly: 25 0 7 0 0 7 0 0 13 7 0 0 7 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 7 19 0 0 0 0 13 0 0 0 7 0 0 0 7 % I
% Lys: 7 0 13 13 7 0 0 7 0 0 0 0 0 0 44 % K
% Leu: 0 0 13 13 7 0 0 0 0 0 0 7 38 13 0 % L
% Met: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 13 13 7 13 0 0 7 7 % N
% Pro: 0 13 0 7 0 13 38 19 32 19 0 0 25 32 7 % P
% Gln: 0 50 13 32 7 7 0 0 0 0 7 0 0 0 0 % Q
% Arg: 0 7 32 13 0 0 7 0 0 0 0 0 0 7 7 % R
% Ser: 19 0 0 0 13 19 13 0 19 13 0 19 13 7 13 % S
% Thr: 0 7 13 0 7 7 0 13 13 0 0 7 0 0 0 % T
% Val: 13 0 0 13 19 0 0 0 7 7 0 13 13 19 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _