Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAC14 All Species: 42.73
Human Site: Y429 Identified Species: 62.67
UniProt: Q08AM6 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08AM6 NP_060522.3 782 87973 Y429 L K W L Y H L Y I K T P R K M
Chimpanzee Pan troglodytes XP_001170940 782 87966 Y429 L K W L Y H L Y I K T P R K M
Rhesus Macaque Macaca mulatta XP_001106962 782 87966 Y429 L K W L Y H L Y I K T P R K M
Dog Lupus familis XP_546837 783 88300 Y430 L K W L Y H L Y I K T P R K M
Cat Felis silvestris
Mouse Mus musculus Q80WQ2 782 88029 Y429 L K W L Y H L Y I K T P R K M
Rat Rattus norvegicus Q80W92 783 88049 Y430 L K W L Y H L Y I K T P R K M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506866 755 85069 Y402 L K W L Y H L Y I K T P R K M
Chicken Gallus gallus Q5ZIW5 780 87805 Y429 L K W L Y H L Y I K T P R K M
Frog Xenopus laevis Q68F38 782 88899 Y431 L K W L Y H L Y I K T P R K M
Zebra Danio Brachydanio rerio Q66L58 771 87538 Y433 L K W L Y H L Y I K T P R K M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650208 687 78014 T365 L T H N S M H T K I A V L K W
Honey Bee Apis mellifera XP_396938 661 75158 K339 Q T K V A V L K W I H H L F I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784614 749 84020 H397 L Q W I Y H L H I K T P K K I
Poplar Tree Populus trichocarpa XP_002314784 724 81260 V393 L S D P S D E V V L L V L E V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_565275 743 83893 D409 V H A G V A K D P Q H F R Q L
Baker's Yeast Sacchar. cerevisiae Q06708 880 99754 S445 L L K L L S D S D P H I T E I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 96.4 N.A. 94.1 94.5 N.A. 80 85.1 81 80.9 N.A. 44.3 47.7 N.A. 55.7
Protein Similarity: 100 99.8 99.6 97.3 N.A. 96.4 96.1 N.A. 84.6 90.6 88.2 88.6 N.A. 61.8 64.9 N.A. 69.4
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 13.3 6.6 N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 13.3 20 N.A. 100
Percent
Protein Identity: 30 N.A. N.A. 29.8 27.9 N.A.
Protein Similarity: 48.7 N.A. N.A. 47.3 48 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: 26.6 N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 7 7 0 0 0 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 7 7 7 7 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 7 0 0 0 0 0 0 13 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 7 0 7 0 % F
% Gly: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 7 7 0 0 69 7 7 0 0 19 7 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 69 13 0 7 0 0 19 % I
% Lys: 0 63 13 0 0 0 7 7 7 69 0 0 7 75 0 % K
% Leu: 88 7 0 69 7 0 75 0 0 7 7 0 19 0 7 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 63 % M
% Asn: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 7 0 0 0 0 7 7 0 69 0 0 0 % P
% Gln: 7 7 0 0 0 0 0 0 0 7 0 0 0 7 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 69 0 0 % R
% Ser: 0 7 0 0 13 7 0 7 0 0 0 0 0 0 0 % S
% Thr: 0 13 0 0 0 0 0 7 0 0 69 0 7 0 0 % T
% Val: 7 0 0 7 7 7 0 7 7 0 0 13 0 0 7 % V
% Trp: 0 0 69 0 0 0 0 0 7 0 0 0 0 0 7 % W
% Tyr: 0 0 0 0 69 0 0 63 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _