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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIGLEC14
All Species:
0.3
Human Site:
S390
Identified Species:
1.67
UniProt:
Q08ET2
Number Species:
4
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08ET2
NP_001092082.1
396
43970
S390
R
C
G
G
P
Q
Q
S
R
A
E
R
P
G
_
Chimpanzee
Pan troglodytes
Q64JA4
387
42507
Rhesus Macaque
Macaca mulatta
XP_001114886
567
62515
D390
R
Y
K
S
S
Q
G
D
S
K
K
M
G
T
G
Dog
Lupus familis
XP_533599
629
69179
S465
S
L
T
V
T
S
S
S
E
G
P
W
A
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91Y57
467
51871
V396
P
H
P
D
A
L
K
V
S
V
S
Q
N
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.9
63.1
37.8
N.A.
40.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63.1
65.4
46
N.A.
55.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
13.3
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
26.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
0
0
0
0
20
0
0
20
0
0
% A
% Cys:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
0
0
0
20
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
20
0
20
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
20
20
0
0
20
0
0
20
0
0
20
20
20
% G
% His:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
20
0
0
0
20
0
0
20
20
0
0
0
0
% K
% Leu:
0
20
0
0
0
20
0
0
0
0
0
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
20
20
0
% N
% Pro:
20
0
20
0
20
0
0
0
0
0
20
0
20
20
0
% P
% Gln:
0
0
0
0
0
40
20
0
0
0
0
20
0
0
0
% Q
% Arg:
40
0
0
0
0
0
0
0
20
0
0
20
0
0
0
% R
% Ser:
20
0
0
20
20
20
20
40
40
0
20
0
0
0
20
% S
% Thr:
0
0
20
0
20
0
0
0
0
0
0
0
0
20
0
% T
% Val:
0
0
0
20
0
0
0
20
0
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% W
% Tyr:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% _