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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSUN2
All Species:
31.52
Human Site:
Y222
Identified Species:
57.78
UniProt:
Q08J23
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08J23
NP_060225.4
767
86471
Y222
D
V
D
N
K
R
C
Y
L
L
V
H
Q
A
K
Chimpanzee
Pan troglodytes
XP_517620
767
86455
Y222
D
V
D
N
K
R
C
Y
L
L
V
H
Q
A
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535800
780
87547
Y224
D
V
D
N
K
R
C
Y
L
L
V
H
Q
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q1HFZ0
757
85433
Y222
D
V
D
N
K
R
C
Y
L
L
V
H
Q
A
K
Rat
Rattus norvegicus
NP_001101873
782
88072
Y247
D
V
D
N
K
R
C
Y
L
L
V
H
Q
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521204
837
94743
Y265
D
V
D
N
K
R
C
Y
L
L
V
H
Q
A
K
Chicken
Gallus gallus
Q5ZLV4
796
90826
Y222
D
V
D
N
K
R
C
Y
L
L
V
H
Q
A
K
Frog
Xenopus laevis
Q4V7N2
698
80033
L196
T
A
Q
I
I
E
M
L
H
A
D
M
N
V
P
Zebra Danio
Brachydanio rerio
NP_956005
706
79550
I170
K
R
L
N
S
P
C
I
M
V
V
N
H
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4M9
746
84143
Y223
D
V
D
N
N
R
C
Y
M
L
V
H
Q
A
K
Honey Bee
Apis mellifera
XP_395050
725
83777
G212
E
G
N
S
L
P
E
G
F
V
I
A
N
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850024
808
89794
N232
D
V
D
F
K
R
S
N
L
L
I
H
Q
T
K
Baker's Yeast
Sacchar. cerevisiae
P38205
684
77860
Q182
A
P
G
S
K
T
A
Q
L
I
E
A
L
H
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
85.9
N.A.
86.8
84.1
N.A.
72.4
72.3
69.4
65.1
N.A.
43.5
42.3
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
90.1
N.A.
90.7
88.6
N.A.
78.3
80.1
78.8
73.4
N.A.
60
60.8
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
0
20
N.A.
86.6
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
0
40
N.A.
93.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.3
34.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
8
0
0
8
0
16
0
62
8
% A
% Cys:
0
0
0
0
0
0
70
0
0
0
0
0
0
0
0
% C
% Asp:
70
0
70
0
0
0
0
0
0
0
8
0
0
16
0
% D
% Glu:
8
0
0
0
0
8
8
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
70
8
8
0
% H
% Ile:
0
0
0
8
8
0
0
8
0
8
16
0
0
0
0
% I
% Lys:
8
0
0
0
70
0
0
0
0
0
0
0
0
0
77
% K
% Leu:
0
0
8
0
8
0
0
8
70
70
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
8
0
16
0
0
8
0
0
0
% M
% Asn:
0
0
8
70
8
0
0
8
0
0
0
8
16
0
0
% N
% Pro:
0
8
0
0
0
16
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
8
0
0
0
0
70
0
0
% Q
% Arg:
0
8
0
0
0
70
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
16
8
0
8
0
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% T
% Val:
0
70
0
0
0
0
0
0
0
16
70
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _