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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBBP4 All Species: 57.88
Human Site: S245 Identified Species: 79.58
UniProt: Q09028 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q09028 NP_001128727.1 425 47656 S245 L H E S L F G S V A D D Q K L
Chimpanzee Pan troglodytes XP_513286 513 56820 S333 L H E S L F G S V A D D Q K L
Rhesus Macaque Macaca mulatta XP_001090071 425 47653 S245 L H E S L F G S V A D D Q K L
Dog Lupus familis XP_864405 410 46140 V233 H T A V V E D V S W H L L H E
Cat Felis silvestris
Mouse Mus musculus Q60972 425 47636 S245 L H E S L F G S V A D D Q K L
Rat Rattus norvegicus Q5XI13 445 49150 S248 W T P T D G G S W N V D Q R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509028 425 47782 S245 L H E S L F G S V A D D Q K L
Chicken Gallus gallus Q9W7I5 425 47588 S245 L H E S L F G S V A D D Q K L
Frog Xenopus laevis Q6INH0 425 47620 S245 L H E S L F G S V A D D Q K L
Zebra Danio Brachydanio rerio Q6P3H7 424 47632 S245 L H E S L F G S V A D D Q K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24572 430 48616 S249 L H E S L F G S V A D D Q K L
Honey Bee Apis mellifera XP_624580 427 48157 S246 L H E S L F G S V A D D Q K L
Nematode Worm Caenorhab. elegans P90916 417 47148 S240 L H D G V F G S V G D D K K L
Sea Urchin Strong. purpuratus XP_780271 430 48569 S246 L H E S L F G S V A D D Q K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22467 424 48176 S245 R H E Y L F G S V G D D Q Y L
Baker's Yeast Sacchar. cerevisiae P39984 401 45042 T226 F N K D L F G T V S E D S L L
Red Bread Mold Neurospora crassa Q7S7N3 446 50382 V260 V K S W I G T V S D D L T L Q
Conservation
Percent
Protein Identity: 100 82.8 99.7 95.5 N.A. 99.7 23.1 N.A. 99 99.7 99 96.7 N.A. 88.5 91.3 70.8 90.4
Protein Similarity: 100 82.8 99.7 96 N.A. 100 39.3 N.A. 99.7 99.7 99.5 97.8 N.A. 95.1 96 82.8 94.1
P-Site Identity: 100 100 100 0 N.A. 100 26.6 N.A. 100 100 100 100 N.A. 100 100 66.6 100
P-Site Similarity: 100 100 100 6.6 N.A. 100 40 N.A. 100 100 100 100 N.A. 100 100 86.6 100
Percent
Protein Identity: N.A. N.A. N.A. 65.6 36.2 47.3
Protein Similarity: N.A. N.A. N.A. 78.8 55 66.5
P-Site Identity: N.A. N.A. N.A. 73.3 40 6.6
P-Site Similarity: N.A. N.A. N.A. 73.3 73.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 6 0 0 0 0 0 0 65 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 6 6 6 0 6 0 0 6 83 89 0 0 0 % D
% Glu: 0 0 71 0 0 6 0 0 0 0 6 0 0 0 6 % E
% Phe: 6 0 0 0 0 83 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 6 0 12 89 0 0 12 0 0 0 0 0 % G
% His: 6 77 0 0 0 0 0 0 0 0 6 0 0 6 0 % H
% Ile: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 6 6 0 0 0 0 0 0 0 0 0 6 71 0 % K
% Leu: 71 0 0 0 77 0 0 0 0 0 0 12 6 12 83 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 6 0 0 0 0 0 0 0 6 0 0 0 0 0 % N
% Pro: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 6 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 77 0 6 % Q
% Arg: 6 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % R
% Ser: 0 0 6 65 0 0 0 83 12 6 0 0 6 0 0 % S
% Thr: 0 12 0 6 0 0 6 6 0 0 0 0 6 0 0 % T
% Val: 6 0 0 6 12 0 0 12 83 0 6 0 0 0 0 % V
% Trp: 6 0 0 6 0 0 0 0 6 6 0 0 0 0 0 % W
% Tyr: 0 0 0 6 0 0 0 0 0 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _