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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC8
All Species:
17.88
Human Site:
S1126
Identified Species:
39.33
UniProt:
Q09428
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q09428
NP_000343.2
1581
177008
S1126
S
I
L
N
R
F
S
S
D
C
N
T
I
D
Q
Chimpanzee
Pan troglodytes
XP_508310
1551
173975
S1096
S
I
L
N
R
F
S
S
D
C
N
T
I
D
Q
Rhesus Macaque
Macaca mulatta
XP_001088694
1581
176783
S1126
S
I
L
N
R
F
S
S
D
C
N
T
I
D
Q
Dog
Lupus familis
XP_542520
1543
172550
A1126
S
I
L
N
R
F
S
A
D
C
N
T
I
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
P70170
1546
174220
P1105
N
I
I
D
Q
H
I
P
P
T
L
E
S
L
T
Rat
Rattus norvegicus
Q09429
1582
177166
S1127
S
I
L
N
R
F
S
S
D
C
N
T
I
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F364
1525
170953
K1072
N
L
V
S
R
F
S
K
E
I
D
T
I
D
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001166118
1581
177105
S1126
S
I
L
N
R
F
S
S
D
T
N
T
I
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
K876
H
L
R
N
L
Y
L
K
T
S
R
D
L
K
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7GB25
1514
168556
I1052
R
I
L
N
R
V
S
I
D
Q
S
V
V
D
L
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
N1055
R
I
L
N
R
F
S
N
D
I
Y
K
V
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
98.4
92.7
N.A.
67.3
95.6
N.A.
N.A.
31.8
N.A.
76.2
N.A.
29.4
N.A.
N.A.
N.A.
Protein Similarity:
100
97.3
98.9
94.6
N.A.
79.9
97.1
N.A.
N.A.
52
N.A.
85.1
N.A.
46.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
6.6
100
N.A.
N.A.
40
N.A.
93.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
33.3
100
N.A.
N.A.
80
N.A.
93.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
29.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.9
52.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
46
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
73
0
10
10
0
82
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
73
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
82
10
0
0
0
10
10
0
19
0
0
64
0
0
% I
% Lys:
0
0
0
0
0
0
0
19
0
0
0
10
0
10
0
% K
% Leu:
0
19
73
0
10
0
10
0
0
0
10
0
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
82
0
0
0
10
0
0
55
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
55
% Q
% Arg:
19
0
10
0
82
0
0
0
0
0
10
0
0
0
10
% R
% Ser:
55
0
0
10
0
0
82
46
0
10
10
0
10
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
10
19
0
64
0
0
10
% T
% Val:
0
0
10
0
0
10
0
0
0
0
0
10
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _