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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC8
All Species:
28.18
Human Site:
S1422
Identified Species:
62
UniProt:
Q09428
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q09428
NP_000343.2
1581
177008
S1422
H
T
L
R
S
R
L
S
I
I
L
Q
D
P
V
Chimpanzee
Pan troglodytes
XP_508310
1551
173975
S1392
H
T
L
R
S
R
L
S
I
I
L
Q
D
P
V
Rhesus Macaque
Macaca mulatta
XP_001088694
1581
176783
S1422
H
T
L
R
S
R
L
S
I
I
L
Q
D
P
V
Dog
Lupus familis
XP_542520
1543
172550
I1404
T
F
E
G
R
I
I
I
D
G
I
D
I
A
K
Cat
Felis silvestris
Mouse
Mus musculus
P70170
1546
174220
S1387
H
T
L
R
S
R
L
S
I
I
L
Q
D
P
I
Rat
Rattus norvegicus
Q09429
1582
177166
S1423
H
T
L
R
S
R
L
S
I
I
L
Q
D
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F364
1525
170953
T1365
H
D
L
R
F
K
I
T
I
I
P
Q
D
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001166118
1581
177105
S1422
Q
T
L
R
S
R
F
S
I
I
Q
Q
D
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
V1153
E
E
V
K
L
K
E
V
V
S
D
L
P
D
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7GB25
1514
168556
G1346
H
D
L
R
S
R
L
G
I
I
P
Q
D
P
T
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
S1350
Y
D
L
R
H
K
L
S
I
I
P
Q
D
S
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
98.4
92.7
N.A.
67.3
95.6
N.A.
N.A.
31.8
N.A.
76.2
N.A.
29.4
N.A.
N.A.
N.A.
Protein Similarity:
100
97.3
98.9
94.6
N.A.
79.9
97.1
N.A.
N.A.
52
N.A.
85.1
N.A.
46.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
93.3
100
N.A.
N.A.
53.3
N.A.
73.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
80
N.A.
73.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
29.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.9
52.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
28
0
0
0
0
0
0
10
0
10
10
82
10
0
% D
% Glu:
10
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
10
0
10
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
10
0
0
0
10
0
10
0
0
0
0
10
% G
% His:
64
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
19
10
82
82
10
0
10
0
19
% I
% Lys:
0
0
0
10
0
28
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
82
0
10
0
64
0
0
0
46
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
28
0
10
73
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
10
82
0
0
10
% Q
% Arg:
0
0
0
82
10
64
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
64
0
0
64
0
10
0
0
0
10
0
% S
% Thr:
10
55
0
0
0
0
0
10
0
0
0
0
0
0
10
% T
% Val:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
37
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _